• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Infection and immunity >Serotypes of bovine rotaviruses distinguished by serum neutralization.
【24h】

Serotypes of bovine rotaviruses distinguished by serum neutralization.

机译：牛轮状病毒的血清型以血清中和为特征。

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Fourteen cytopathic bovine rotaviruses isolated from naturally affected calves were characterized serologically by serum neutralization. Antisera were prepared in guinea pigs against the three isolates and the Lincoln strain of bovine rotavirus. These four rotaviruses were segregated into at least two distinct serotypes (designated types 1 and 2) by serum neutralization. The remaining 11 isolates were also placed into two groups according to neutralization specificity by using the antisera against types 1 and 2 bovine rotavirus. When colostrum-deprived calves were experimentally inoculated with type 1 or 2 bovine rotavirus, respectively, the calves produced neutralizing antibodies against the inoculated serotype but not against the other serotype. Calf sera obtained from six herds with naturally occurring rotavirus infections possessed neutralizing antibodies against type 1 or 2 or both. Thus, distinct serotypes of bovine rotavirus were demonstrated by serum neutralization. The possible role of serotypes in the epidemiology of rotavirus infection among bovine species is discussed.
机译：通过血清中和从血清学上鉴定了十四种从自然感染的牛犊中分离出的细胞性牛轮状病毒。在豚鼠中制备针对三种分离物和牛轮状病毒林肯菌株的抗血清。通过血清中和将这四种轮状病毒分离成至少两种不同的血清型（称为1型和2型）。通过使用针对1型和2型牛轮状病毒的抗血清，根据中和特异性，将其余的11个分离株也分为两组。当分别用1型或2型牛轮状病毒分别对初乳剥夺的小牛进行实验接种时，小牛会产生针对接种的血清型的中和抗体，而不针对其他血清型。从六群自然发生轮状病毒感染的牛群中获得的小牛血清具有针对1型或2型或两者的中和抗体。因此，通过血清中和证实了牛轮状病毒的不同血清型。讨论了血清型在牛轮状病毒感染流行病学中的可能作用。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号