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首页> 外文期刊>Infection and immunity >Binding of resting platelets to Candida albicans germ tubes.
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Binding of resting platelets to Candida albicans germ tubes.

机译：静息血小板与白色念珠菌细菌管的结合。

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The binding of resting platelets to Candida albicans germ tubes was studied by means of an affinity column in which germ tubes were physically immobilized. Adhesion of platelets to the column was dependent on both the germ tube concentration and the number of platelets applied. It was found that the interaction of C. albicans germ tubes with platelets is specific and should be mediated by a fungal protein receptor. The results obtained by scanning electron microscopy confirmed that resting platelets can fix directly onto germ tubes. In addition, this study showed that attachment of platelets onto C. albicans is associated with morphological changes. Platelets lost their discoid shape, became globular, generated spikes or pseudopods, and then flattened on the yeast cells.
机译：通过亲和柱研究静止的血小板与白色念珠菌细菌管的结合，亲和柱物理固定了细菌管。血小板对柱的粘附性取决于胚管浓度和施加的血小板数量。已发现白色念珠菌胚管与血小板的相互作用是特异性的，并应由真菌蛋白受体介导。通过扫描电子显微镜获得的结果证实静息血小板可以直接固定在胚芽管上。此外，这项研究表明血小板附着在白色念珠菌上与形态变化有关。血小板失去盘状形状，变成球状，产生尖峰或假足，然后在酵母细胞上变平。

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