Growth inhibition of oral streptococci in saliva by anionic proteins from two caries-free individuals.

R A Cowman; S S Baron; R J Fitzgerald; J L Danziger; J A Quintana

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Growth inhibition of oral streptococci in saliva by anionic proteins from two caries-free individuals.

机译：来自两个无龋个体的阴离子蛋白抑制唾液中口腔链球菌的生长。

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Mixed saliva from two caries-free individuals possessed antimicrobial activity toward Streptococcus mutans and S. sanguis. This inhibitory activity was attributed to the presence of a group of four anionic proteins each of which strongly inhibited the growth of the oral streptococci in a saliva protein-based medium but not in a medium containing amino acids as a nitrogen source. These proteins, with isoelectric points of 4.70, 4.90, 4.98, and 5.05, respectively, neither reacted with antisera to immunoglobulin A, G, or M nor appeared to be functionally related to a number of salivary peroxidases, lactoferrin, or lysozyme. On this basis, they may represent a previously unreported group of growth-inhibitory antimicrobial factors occurring in the saliva of some individuals.

机译：来自两个无龋个体的混合唾液对变形链球菌和血链球菌具有抗菌活性。该抑制活性归因于一组四个阴离子蛋白的存在，它们各自在基于唾液蛋白的培养基中而不在含有氨基酸作为氮源的培养基中强烈抑制口腔链球菌的生长。这些蛋白的等电点分别为4.70、4.90、4.98和5.05，它们既未与抗血清反应生成免疫球蛋白A，G或M，也未与多种唾液过氧化物酶，乳铁蛋白或溶菌酶功能相关。在此基础上，它们可能代表了以前未报道过的某些个体唾液中存在的抑制生长的抗菌因子。

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《Infection and immunity》 |1982年第2期|共6页
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R A Cowman; S S Baron; R J Fitzgerald; J L Danziger; J A Quintana;
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中图分类医学免疫学;
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1. Immunological cross-reactivity of anionic proteins from caries-free and caries-active salivas which differ in biological properties toward oral streptococci. [J] . S D Obenauf, R A Cowman, R J Fitzgerald Infection and immunity . 1986,第2期

机译：来自无龋和有龋活性唾液的阴离子蛋白的免疫交叉反应性，其生物学特性与口服链球菌不同。
2. Aggregation of Oral Streptococci Selected by Growth on Human Saliva from Different Glands [J] . A. J. M. Ligtenberg, P. J. M. Camp, J. S. Van Der Hoeven, Microbial Ecology in Health and Disease . 1991,第1期

机译：通过在不同腺体的唾液上生长选择的口腔链球菌聚集
3. Cumulative correlations of lysozyme, lactoferrin, peroxidase, S-IgA, amylase, and total protein concentrations with adherence of oral viridans streptococci to microplates coated with human saliva. [J] . Rudney JD, Hickey KL, Ji Z Journal of Dental Research: Official Publication of the International Association for Dental Research . 1999,第3期

机译：溶菌酶，乳铁蛋白，过氧化物酶，S-IgA，淀粉酶和总蛋白浓度与口服绿藻链球菌对涂有人类唾液的微孔板的粘附力的累积相关性。
4. Discovery and validation of serum and saliva protein biomarkers for human oral cancer [C] . Shen Hu, Martha Arellano-Garcia, Pinmanee Boontheung, ASMS Conference on Mass Spectrometry and Allied Topics . 2007

机译：对人口腔癌血清和唾液蛋白生物标志物的发现与验证
5. Retrospective evaluation of microbial presence in existing saliva repository: A PCR based molecular survey of oral microbial populations from existing saliva samples. [D] . Davis, Jay Ericksen. 2011

机译：回顾性评估现有唾液库中微生物的存在：基于PCR的现有唾液样本中口腔微生物种群的分子调查。
6. Growth inhibition of oral streptococci in saliva by anionic proteins from two caries-free individuals. [O] . R A Cowman, S S Baron, R J Fitzgerald, 1982

机译：来自两个无龋个体的阴离子蛋白抑制唾液中口腔链球菌的生长。
7. Inhibition of Oral Streptococci Growth Induced by the Complementary Action of Berberine Chloride and Antibacterial Compounds [O] . Arkadiusz Dziedzic, Robert D. Wojtyczka, Robert Kubina 2015

机译：氯化小檗碱与抗菌化合物互补作用对口腔链球菌生长的抑制作用
8. Cell Surface Proteins of Animal Group C Streptococci Mediating Binding of PlasmaProteins [R] . Jonsson, H. 1994

机译：动物群C链球菌的细胞表面蛋白介导血浆蛋白的结合

Growth inhibition of oral streptococci in saliva by anionic proteins from two caries-free individuals.

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