首页> 外文期刊>Infection and immunity >Temperature-dependent transcriptional regulation of expression of fimbriae in an Escherichia coli strain isolated from a child with severe enteritis.
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Temperature-dependent transcriptional regulation of expression of fimbriae in an Escherichia coli strain isolated from a child with severe enteritis.

机译:分离自患有严重肠炎的儿童的大肠杆菌菌株中菌毛表达的温度依赖性转录调控。

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摘要

Escherichia coli 469-3 synthesizes fibrillar fimbriae at 37 degrees C, but not at 18 degrees C, which promote its adherence to human colonocytes. RNA homologous with a cloned fragment of the strain 469-3 chromosome necessary for normal expression of fimbriae was virtually undetectable in bacteria grown at 18 degrees C, indicating that environmental temperature affects expression by regulating transcription.
机译:大肠杆菌469-3在37℃而不是18℃下合成原纤维菌毛,这促进了其对人结肠细胞的粘附。正常表达菌毛所必需的与469-3染色体的克隆片段同源的RNA在18摄氏度下生长的细菌中几乎无法检测到,表明环境温度通过调节转录影响表达。

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