Role of catechol siderophore synthesis in Vibrio vulnificus virulence.

C M Litwin; T W Rayback; J Skinner

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Role of catechol siderophore synthesis in Vibrio vulnificus virulence.

机译：邻苯二酚铁载体合成在创伤弧菌毒力中的作用。

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We isolated a Vibrio vulnificus TnphoA mutant that was unable to produce catechol siderophores or to acquire iron from transferrin. This mutant showed reduced virulence in an infant mouse model. The TnphoA insertion was in an open reading frame designated venB. The venB gene cloned on a plasmid restored catechol production to the mutant. The deduced amino acid sequence of venB is 41% identical to the enzyme isochorismatase of Escherichia coli (EntB), an enzyme involved in the biosynthesis of the catechol siderophore enterobactin.

机译：我们分离了一个创伤弧菌TnphoA突变体，该突变体无法产生邻苯二酚铁载体或无法从转铁蛋白中获得铁。该突变体在婴儿小鼠模型中显示出降低的毒力。 TnphoA插入位于一个名为venB的开放阅读框中。克隆在质粒上的venB基因使邻苯二酚恢复为突变体。推导的venB氨基酸序列与大肠杆菌（EntB）的等轴线酶（EntB）是一种41％相同，该酶参与了邻苯二酚铁载体肠杆菌素的生物合成。

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《Infection and immunity》 |1996年第7期|共5页
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C M Litwin; T W Rayback; J Skinner;
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1. Role of catechol siderophore synthesis in Vibrio vulnificus virulence. [J] . C M Litwin, T W Rayback, J Skinner Infection and immunity . 1996,第7期

机译：邻苯二酚铁载体合成在创伤弧菌毒力中的作用。
2. Nonribosomal Peptide Synthetase is Responsible for the Biosynthesis of Siderophore in Vibrio vulnificus MO6-24/O [J] . Kim In Hwang, Jung-Im Shim, Ko-Eun Lee, Journal of microbiology and biotechnology . 2008,第1期

机译：非核糖体肽合成酶负责创伤弧菌MO6-24 / O中铁载体的生物合成。
3. The Vibrio cholerae VctPDGC system transports catechol siderophores and a siderophore-free iron ligand. [J] . Wyckoff EE, Payne SM Molecular Microbiology . 2011,第6期

机译：霍乱弧菌VctPDGC系统可转运邻苯二酚铁载体和不含铁载体的铁配体。
4. Characterization of components of type IV pili and type II extracellular secretion in Vibrio vulnificus and determination of their role in virulence [C] . Mark S. Strom, Rohinee N. Paranjpye U.S.-Japan Meeting on Aquaculture . 2001

机译：IV型pili和II型细胞外分泌组分的表征，vibrio wharnificus和毒力中作用的测定
5. An investigation of the role of vibrio vulnificus rbdA and vibrio parahaemolyticus sypA in biofilm formation [D] . Thompson, Cecilia Margaret. 2014

机译：创伤弧菌rbdA和副溶血弧菌sypA在生物膜形成中的作用研究
6. Role of catechol siderophore synthesis in Vibrio vulnificus virulence. [O] . C M Litwin, T W Rayback, J Skinner 1996

机译：邻苯二酚铁载体合成在弧菌弧菌毒力中的作用。
7. Role of catechol siderophore synthesis in Vibrio vulnificus virulence [O] . C M Litwin, T W Rayback, J Skinner 1996

机译：儿茶酚筒合成在vibrio vulnfificus毒力中的作用

Role of catechol siderophore synthesis in Vibrio vulnificus virulence.

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