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Alteration of gonococcal protein expression in acidic culture.

机译:酸性培养中淋球菌蛋白表达的变化。

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摘要

We grew Neisseria gonorrhoeae under acidic, neutral, and alkaline conditions and noted altered expression of at least 12 outer membrane proteins between 31 and 100 kDa in size. One protein whose expression was upregulated under acidic conditions was gonococcal heat shock protein 63. These proteins may contribute to the pathogenesis of gonorrhea in the urogenital tract.
机译:我们在酸性,中性和碱性条件下培养了淋病奈瑟氏球菌,并注意到大小在31至100 kDa之间的至少12种外膜蛋白的表达发生了变化。淋病球菌热休克蛋白63是一种在酸性条件下表达上调的蛋白。这些蛋白可能与泌尿生殖道淋病的发病机理有关。

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