Interactions of human mannose-binding protein with lipoteichoic acids.

V Y Polotsky; W Fischer; R A Ezekowitz; K A Joiner

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Interactions of human mannose-binding protein with lipoteichoic acids.

机译：人甘露糖结合蛋白与脂蛋白酸的相互作用。

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We explored the interaction of human recombinant mannose-binding protein and lipoteichoic acids (LTAs) by enzyme-linked immunosorbent assay. The best ligand was Micrococcus luteus lipomannan, followed by Enterococcus spp. LTA containing mono-, di-, and oligoglucosyl substituents. LTAs lacking terminal sugars (those of Streptococcus pyogenes and Staphylococcus aureus) or containing galactosyl substituents (those of Listeria spp. and Lactococcus spp.) were poor ligands. These results are consistent with known structural requirements for binding through the mannose-binding protein carbohydrate recognition domain.

机译：我们通过酶联免疫吸附试验探索了人类重组甘露糖结合蛋白和脂蛋白酸（LTAs）的相互作用。最好的配体是黄褐微球菌脂质体，其次是肠球菌。含有单，二和低聚葡萄糖基取代基的LTA。缺少末端糖（化脓性链球菌和金黄色葡萄球菌的那些）或含有半乳糖基取代基（李斯特菌和乳球菌的那些）的LTA是较差的配体。这些结果与通过甘露糖结合蛋白碳水化合物识别结构域结合的已知结构要求一致。

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《Infection and immunity》 |1996年第1期|共4页
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V Y Polotsky; W Fischer; R A Ezekowitz; K A Joiner;
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中图分类医学免疫学;
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2. Unravelling the interactions of the environmental host Acanthamoeba castellanii with fungi through the recognition by mannose-binding proteins [J] . Goncalves Diego de Souza, Ferreira Marina da Silva, Gomes Kamilla Xavier, Cellular microbiology . 2019,第10期

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3. Lectin-Carbohydrate Interactions: Fine Specificity Difference Between Two Mannose-Binding Proteins [J] . Reiko T. Lee, Yasuro Shinohara, Yukio Hasegawa, Bioscience Reports . 1999,第4期

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5. Thermodynamic characterizations of coulombic end effects and coupled folding effects on binding of cationic oligopeptides to nucleic acids. Two-domain of preferential solute-protein interactions. [D] . Zhang, Wentao. 1996

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6. Interactions of human mannose-binding protein with lipoteichoic acids. [O] . V Y Polotsky, W Fischer, R A Ezekowitz, 1996

机译：人甘露糖结合蛋白与脂蛋白酸的相互作用。
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Interactions of human mannose-binding protein with lipoteichoic acids.

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