Host Resistance to Listeria monocytogenes Infection Is Enhanced but Resistance to Staphylococcus aureus Infection Is Reduced in Acute Graft-versus-Host Disease in Mice

Tomisato Miura; Daisuke Mizuki; Sanae Sasaki; Suguru Hasegawa; Hiroshi Sashinami; Akio Nakane

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Host Resistance to Listeria monocytogenes Infection Is Enhanced but Resistance to Staphylococcus aureus Infection Is Reduced in Acute Graft-versus-Host Disease in Mice

机译：在小鼠急性移植物抗宿主病中，宿主对单核细胞增生李斯特菌感染的抗性增强，但对金黄色葡萄球菌感染的抗性降低。

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Acute graft-versus-host disease (GVHD) is characterized by the production of high levels of T helper 1 (Th1)-type cytokines. Bone marrow transplantation from allogeneic C57BL/6 cells to CBF1 mice produced acute GVHD. Host resistance to Th1-driven Listeria monocytogenes was enhanced, whereas host resistance to Th2-driven Staphylococcus aureus was reduced during acute GVHD. These results suggest that opposite host responses are observed between Th1-driven and Th2-driven bacterial infections in acute GVHD.

机译：急性移植物抗宿主病（GVHD）的特征是高水平的T辅助1（Th1）型细胞因子的产生。从同种异体C57BL / 6细胞向CBF1小鼠进行骨髓移植可产生急性GVHD。在急性GVHD期间，宿主对Th1驱动的单核细胞增生李斯特菌的抗药性增强，而宿主对Th2驱动的金黄色葡萄球菌的抗药性降低。这些结果表明在急性GVHD中，在Th1驱动和Th2驱动的细菌感染之间观察到相反的宿主反应。

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《Infection and immunity》 |2000年第7期|共4页
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Tomisato Miura; Daisuke Mizuki; Sanae Sasaki; Suguru Hasegawa; Hiroshi Sashinami; Akio Nakane;
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1. Host Resistance to Listeria monocytogenes Infection Is Enhanced but Resistance to Staphylococcus aureus Infection Is Reduced in Acute Graft-versus-Host Disease in Mice [J] . Tomisato Miura, Daisuke Mizuki, Sanae Sasaki, Infection and immunity . 2000,第7期

机译：在小鼠急性移植物抗宿主病中，宿主对单核细胞增生李斯特菌感染的抗性增强，但对金黄色葡萄球菌感染的抗性降低。
2. Thalidomide enhances both primary and secondary host resistances to Listeria monocytogenes infection by a neutrophil-related mechanism in female B6C3F1 mice. [J] . Guo TL, Chi RP, Karrow NA, Toxicology and Applied Pharmacology . 2005,第3期

机译：沙利度胺通过雌性B6C3F1小鼠中性粒细胞相关机制增强对单核细胞增生李斯特菌感染的主要和次要宿主抗性。
3. Comparison of Host Resistance to Primary and Secondary Listeria monocytogenes Infections in Mice by Intranasal and Intravenous Routes [J] . Mayuko Mizuki, Akio Nakane, Kenji Sekikawa, Infection and immunity . 2002,第9期

机译：通过鼻腔和静脉途径比较小鼠对小鼠原发性和继发性李斯特菌感染的抵抗力
4. ANTIMICROBIAL RESISTANCE PATTERNS OF STAPHYLOCOCCUS AUREUS ISOLATED FROM INTRAMAMMARY INFECTIONS BEFORE AND AFTER THE DRY PERIOD OF DAIRY CATTLE IN CANADA [C] . K.E. Leslie, Y.H. Schukken, M. Archambault, Annual Meeting of the National Mastitis Council . 2003

机译：在加拿大奶牛牛奶牛后甲型内感染的金黄色葡萄球菌的抗菌抗性模式
5. Resistant Staphylococcus aureus infections in the United States: A new classification, a new resistance and the implications for surveillance, prevention, and control. [D] . Sievert, Dawn M. 2008

机译：美国耐药性金黄色葡萄球菌感染：新的分类，耐药性及其对监测，预防和控制的意义。
6. Note: Host Resistance to Listeria monocytogenes Infection Is Enhanced but Resistance to Staphylococcus aureus Infection Is Reduced in Acute Graft-versus-Host Disease in Mice [O] . Tomisato Miura, Daisuke Mizuki, Sanae Sasaki, 2000

机译：注意：在小鼠急性移植物抗宿主病中宿主对单核细胞增生性李斯特菌感染的抗性增强但对金黄色葡萄球菌感染的抗性降低
7. Host Resistance to Listeria monocytogenes Infection Is Enhanced but Resistance to Staphylococcus aureus Infection Is Reduced in Acute Graft-versus-Host Disease in Mice [O] . Miura, Tomisato, Mizuki, Daisuke, Sasaki, Sanae, 2000

机译：在小鼠急性移植物抗宿主病中，宿主对单核细胞增生李斯特菌感染的抗性增强，但对金黄色葡萄球菌感染的抗性降低。

Host Resistance to Listeria monocytogenes Infection Is Enhanced but Resistance to Staphylococcus aureus Infection Is Reduced in Acute Graft-versus-Host Disease in Mice

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