Induction of nonspecific acquired resistance and delayed-type hypersensitivity, but not specific acquired resistance in mice inoculated with killed mycobacterial vaccines.

I M Orme

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Induction of nonspecific acquired resistance and delayed-type hypersensitivity, but not specific acquired resistance in mice inoculated with killed mycobacterial vaccines.

机译：在接种灭活的分枝杆菌疫苗的小鼠中诱导非特异性获得性耐药和迟发型超敏反应，但不引起特异性获得性耐药。

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A number of nonliving mycobacterial preparations were tested in vivo for their capacity to generate various relevant parameters of cellular immunity. All preparations tested had some detectable activity in raising resistance to challenge with Mycobacterium tuberculosis or with Listeria monocytogenes and in conferring the ability to mount a delayed-type hypersensitivity response to tuberculin. This report presents the first evidence, however, that none of these preparations were able to generate protective T cells capable of adoptive immunization against virulent tuberculosis. These data are discussed in terms of the use of these preparations in generating M. tuberculosis-reactive T-cell lines and the application of these lines in the continuing search for an improved vaccine against tuberculosis.

机译：在体内测试了许多无生命的分枝杆菌制剂产生各种相关细胞免疫参数的能力。所有测试的制剂在提高抵抗结核分枝杆菌或单核细胞增生李斯特菌的抵抗力以及赋予对结核菌素进行迟发型超敏反应的能力方面具有一定的可检测活性。但是，该报告提供了第一个证据，即这些制剂均不能产生能够过继免疫针对强力结核病的保护性T细胞。根据这些制剂在产生结核分枝杆菌反应性T细胞系中的用途以及在继续寻找改良的抗结核疫苗中的应用来讨论这些数据。

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《Infection and immunity》 |1988年第12期|共3页
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I M Orme;
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中图分类医学免疫学;
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1. Delayed-type hypersensitivity to influenza virus. Induction of antigen-specific suppressor T cells for delayed-type hypersensitivity to hemagglutinin during influenza virus infection in mice. [J] . F Y Liew, S M Russell The Journal of Experomental Medicine . 1980,第4期

机译：对流感病毒的迟发型超敏反应。诱导抗原特异性抑制性T细胞在小鼠流感病毒感染期间对血凝素的迟发型超敏反应。
2. Identification of tobacco ESTs with a hypersensitive response (HR)-specific pattern of expression and likely involved in the induction of the HR and/or localized acquired resistance (LAR) [J] . Ghannam A, Jacques A, De Ruffray P, Plant Physiology and Biochemistry . 2005,第3期

机译：鉴定具有超敏反应（HR）特异性表达模式且可能参与HR诱导和/或局部获得性耐药（LAR）的烟草ESTs
3. The Predictive Validity of Naturally Acquired Delayed-Type Hypersensitivity to Leishmanin in Resistance to Leishmania major-Associated Cutaneous Leishmaniasis. [J] . Ben Salah A, Louzir H, Chlif S, The Journal of Infectious Diseases . 2005,第11期

机译：天然获得的对利什曼宁的迟发型超敏反应在对利什曼原虫主要相关的皮肤利什曼病的抵抗中的预测有效性。
4. Involvement of oxidative burst in systemic signaling for induction of systemic acquired resistance in plants [C] . Noriyuki Doke H.-Jun Park, Hirohumi Yoshioka, Kazuhito Kawakita, Asian conference on plant pathology . 2000

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5. The evaluation of the potential for chlorine dioxide to prime plant defenses for a systemic acquired resistance in light red kidney bean plants inoculated with common bean bacterial wilt [D] . Sandoval, Vanessa Marie 2015

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6. Induction of nonspecific acquired resistance and delayed-type hypersensitivity but not specific acquired resistance in mice inoculated with killed mycobacterial vaccines. [O] . I M Orme 1988

机译：在接种灭活的分枝杆菌疫苗的小鼠中诱导非特异性获得性抗药性和迟发型超敏反应但未诱导特异性抗药性。
7. The predictive validity of naturally acquired delayed-type hypersensitivity to leishmanin in resistance to Leishmania major-associated cutaneous leishmaniasis. [O] . Ben Salah, Afif, Louzir, Hechmi, Chlif, Sadok, 2005

机译：天然获得的对利什曼宁的迟发型超敏反应在对利什曼原虫主要相关性皮肤利什曼病的抵抗中的预测有效性。

Induction of nonspecific acquired resistance and delayed-type hypersensitivity, but not specific acquired resistance in mice inoculated with killed mycobacterial vaccines.

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