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Production of Prostaglandins and Leukotrienes by Pathogenic Fungi

机译:致病真菌生产前列腺素和白三烯

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摘要

These studies demonstrate that pathogenic fungi (dermatophytic, subcutaneous, and systemic) have the ability to produce eicosanoids both from simple metabolites and from arachidonic acid. Host-derived eicosanoids have been previously demonstrated to enhance fungal colonization and atopic disease development. Thus, fungus-derived eicosanoids represent a potential class of novel virulence factors.
机译:这些研究表明,致病真菌(皮肤真菌,皮下和全身性真菌)具有从简单代谢产物和花生四烯酸生产类花生酸的能力。先前已证明宿主来源的类花生酸能增强真菌定植和特应性疾病的发展。因此,真菌衍生的类花生酸代表了新型毒力因子的潜在类别。

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