Revised amino acid sequence for a heat-stable enterotoxin produced by an Escherichia coli strain (18D) that is pathogenic for humans.

M R Thompson; R A Giannella

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Revised amino acid sequence for a heat-stable enterotoxin produced by an Escherichia coli strain (18D) that is pathogenic for humans.

机译：由人类致病的大肠杆菌菌株（18D）产生的热稳定肠毒素的氨基酸序列经修订。

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The amino acid sequence of heat-stable enterotoxin produced by enterotoxigenic Escherichia coli 18D has been revised. Amino acids originally assigned to positions 11 and 18, i.e., Tyr and Asn, respectively, were found to occupy positions 18 and 11, respectively. Thus all heat-stable enterotoxins composed of 18 amino acids sequenced to date from human, porcine, and bovine isolates of E. coli have identical primary structures, i.e., Asn-Thr-Phe-Tyr-Cys-Cys-Glu-Leu-Cys-Cys-Asn-Pro-Ala-Cys-Ala-Gly-Cys-Tyr. Furthermore, all 18- and 19-amino-acid heat-stable enterotoxins from E. coli share an almost identical core sequence, i.e., 14 of the 15 carboxy-terminal amino acid residues are identical.

机译：由产肠毒素大肠杆菌18D产生的热稳定肠毒素的氨基酸序列已被修改。发现最初分配给位置11和18的氨基酸，即分别为Tyr和Asn，占据了位置18和11。因此，迄今从人，猪和牛的大肠杆菌分离物中测序的由18个氨基酸组成的所有热稳定肠毒素均具有相同的一级结构，即Asn-Thr-Phe-Tyr-Cys-Cys-Glu-Leu-Cys -Cys-Asn-Pro-Ala-Cys-Ala-Gly-Cys-Tyr。此外，来自大肠杆菌的所有18和19个氨基酸的热稳定肠毒素都具有几乎相同的核心序列，即15个羧基末端氨基酸残基中的14个是相同的。

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《Infection and immunity》 |1985年第3期|共3页
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M R Thompson; R A Giannella;
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中图分类医学免疫学;
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1. Revised amino acid sequence for a heat-stable enterotoxin produced by an Escherichia coli strain (18D) that is pathogenic for humans. [J] . M R Thompson, R A Giannella Infection and immunity . 1985,第3期

机译：由人类致病的大肠杆菌菌株（18D）产生的热稳定肠毒素的氨基酸序列经修订。
2. Detection of the enteroaggregative Escherichia coli heat-stable enterotoxin 1 gene sequences in enterotoxigenic E. coli strains pathogenic for humans. [J] . T Yamamoto, P Echeverria Infection and immunity . 1996,第4期

机译：在对人类致病的产肠毒素的大肠杆菌菌株中检测肠聚集性大肠杆菌热稳定肠毒素1基因序列。
3. Citrobacter freundii produces an 18-amino-acid heat-stable enterotoxin identical to the 18-amino-acid Escherichia coli heat-stable enterotoxin (ST Ia). [J] . A Guarino, R Giannella, M R Thompson Infection and immunity . 1989,第2期

机译：弗氏柠檬酸杆菌产生的18个氨基酸的热稳定肠毒素与18个氨基酸的大肠杆菌的热稳定肠毒素（ST Ia）相同。
4. A simple clustering approach for pathogenic strain identification based on local and global amino acid compositional signatures from genomic sequences: the Escherichia genus case [C] . Vasilis J. Promponas International Conference on Information Technology and Applications in Biomedicine . 2009

机译：基于基因组序列的局部和全球氨基酸组成特征的病原菌鉴定简单聚类方法：大肠杆菌壳
5. Development of a diagnostic method to allow strain-level identification of Staphylococcus aureus based on the nucleotide sequence of the enterotoxin gene and the amino acid sequence of its enterotoxin [D] . James, Mindy M. 2008

机译：根据肠毒素基因的核苷酸序列及其肠毒素的氨基酸序列，开发一种诊断方法，以菌株级鉴定金黄色葡萄球菌
6. Revised amino acid sequence for a heat-stable enterotoxin produced by an Escherichia coli strain (18D) that is pathogenic for humans. [O] . M R Thompson, R A Giannella 1985

机译：由人类致病的大肠杆菌（18D）产生的热稳定肠毒素的氨基酸序列经修订。
7. Amino acid sequence of a heat-stable enterotoxin isolated from enterotoxigenic Escherichia coli strain 18D [O] . Takao Toshifumi, Hitouji Tetsuo, Aimoto Saburo, 1983

机译：从产肠毒素的大肠埃希氏菌菌株18D中分离出的热稳定肠毒素的氨基酸序列
8. Enteroaggregative Escherichia coli Heat-Stable Enterotoxin 1 Represents AnotherSubfamily of E. coli Heat-Stable Toxin. (Reannouncement with New Availability Information) [R] . Savarino, S. J., Fasano, A., Watson, J., 1993

机译：肠聚集性大肠杆菌热稳定肠毒素1代表另一个大肠杆菌热稳定毒素家族。（重新公布新的可用性信息）

Revised amino acid sequence for a heat-stable enterotoxin produced by an Escherichia coli strain (18D) that is pathogenic for humans.

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