Antigenic switching of TSA 417, a trophozoite variable surface protein, following completion of the life cycle of Giardia lamblia.

T C Meng; M L Hetsko; F D Gillin

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Antigenic switching of TSA 417, a trophozoite variable surface protein, following completion of the life cycle of Giardia lamblia.

机译：贾第鞭毛虫的生命周期完成后，滋养体可变表面蛋白TSA 417的抗原转换。

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Expression of TSA 417, the predominant cysteine-rich variable surface protein of Giardia lamblia WB clone C6 trophozoites, did not change during encystation in vitro. However, in vitro excystation of cysts derived in vitro or in vivo consistently produced TSA 417 nonexpressing trophozoite populations, suggesting that completion of the life cycle leads to antigenic switching.

机译：TSA 417（贾第鞭毛虫WB克隆C6滋养体的主要富含半胱氨酸的可变表面蛋白）的表达在离体过程中未发生变化。然而，体外或体内衍生的囊肿的体外兴奋作用始终产生TSA 417非表达滋养体种群，这表明生命周期的完成会导致抗原转换。

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《Infection and immunity》 |1993年第12期|共4页
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T C Meng; M L Hetsko; F D Gillin;
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中图分类医学免疫学;
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1. A new locus (vsp417-4) belonging to the tsa417-like subfamily of variant-specific surface protein genes in Giardia intestinalis. [J] . Ey PL, Darby JM, Mayrhofer G Molecular and Biochemical Parasitology . 1999,第1期

机译：一个新的基因座（vsp417-4），属于贾第鞭毛虫小肠特异性表面蛋白基因的tsa417-like亚家族。
2. Biology of Giardia lamblia. Detection of N-acetyl-D-glucosamine as the only surface saccharide moiety and identification of two distinct subsets of trophozoites by lectin binding. [J] . H D Ward, J Alroy, B I Lev, The Journal of Experomental Medicine . 1988,第1期

机译：贾第鞭毛虫的生物学。检测N-乙酰基-D-氨基葡萄糖作为唯一的表面糖部分，并通过凝集素结合鉴定滋养体的两个不同子集。
3. Comparative proteomic analysis of trophozoites versus cysts of Giardia lamblia. [J] . Kim J, Bae SS, Sung MH, Parasitology Research . 2009,第2期

机译：贾第鞭毛虫滋养体和囊肿的蛋白质组比较分析。
4. Prediction of antigen epitopes on protein surfaces based on support vector machine [C] . Pingping Sun, Wenhan Chen, Xing Wang, International conference on biotechnology, chemical and materials engineering . 2012

机译：基于支持向量机的蛋白质表面抗原表位预测
5. Assembly and promoter analysis of variant-specific surface protein (VSP) genes of Giardia lamblia. [D] . Nigam, Anuranjini. 2005

机译：贾第鞭毛虫变种特异性表面蛋白（VSP）基因的组装和启动子分析。
6. Antigenic switching of TSA 417 a trophozoite variable surface protein following completion of the life cycle of Giardia lamblia. [O] . T C Meng, M L Hetsko, F D Gillin 1993

机译：贾第鞭毛虫的生命周期完成后滋养体可变表面蛋白TSA 417的抗原转换。
7. Antigenic switching of TSA 417, a trophozoite variable surface protein, following completion of the life cycle of Giardia lamblia [O] . T C Meng, M L Hetsko, F D Gillin 1993

机译：TSA 417的抗原切换，葡萄干羊皮膜生命周期完成后的滋生剂可变表面蛋白
8. Expression of Two Variant Surface Glycoproteins on Individual African Trypanosomes during Antigen Switching [R] . Esser, K. M., Schoenbechler, M. 1985

机译：抗原转换过程中两种变异表面糖蛋白在非洲锥虫上的表达

Antigenic switching of TSA 417, a trophozoite variable surface protein, following completion of the life cycle of Giardia lamblia.

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