Protective immunity induced by outer membrane proteins of Salmonella typhimurium in mice.

V Udhayakumar; V R Muthukkaruppan

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Protective immunity induced by outer membrane proteins of Salmonella typhimurium in mice.

机译：鼠伤寒沙门氏菌外膜蛋白诱导的小鼠保护性免疫。

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Outer membrane proteins (OMP) extracted from both smooth (C5) and rough (Rb2) strains of Salmonella typhimurium were able to induce protective immunity to salmonellosis. The OMP-induced protection lasted for at least 6 months. The antibody level was estimated by passive hemagglutination. In the C5 OMP-immunized mice, antibodies to both proteins and lipopolysaccharide were detected. On the other hand, in the Rb2 OMP-immunized mice, antiprotein but not antilipopolysaccharide antibodies were detected. Delayed-type hypersensitivity appeared as early as the second week after immunization with OMP and persisted through the fourth week.

机译：从鼠伤寒沙门氏菌的平滑菌株（C5）和粗糙菌株（Rb2）提取的外膜蛋白（OMP）能够诱导沙门氏菌的保护性免疫。 OMP诱导的保护持续至少6个月。通过被动血凝估计抗体水平。在经C5 OMP免疫的小鼠中，检测到针对蛋白质和脂多糖的抗体。另一方面，在Rb2 OMP免疫的小鼠中，检测到抗蛋白但未检测到抗脂多糖抗体。迟发型超敏反应最早出现在OMP免疫后的第二周，并持续到第四周。

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《Infection and immunity》 |1987年第3期|共6页
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V Udhayakumar; V R Muthukkaruppan;
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中图分类医学免疫学;
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1. Outer membrane vesicles derived from Salmonella Typhimurium mutants with truncated LPS induce cross-protective immune responses against infection of Salmonella enterica serovars in the mouse model [J] . Liu Qiong, Liu Qing, Yi Jie, International journal of medical microbiology: IJMM . 2016,第8期

机译：鼠伤寒沙门氏菌突变体具有截短的LPS衍生的外膜囊泡在小鼠模型中诱导针对肠炎沙门氏菌感染的交叉保护性免疫应答。
2. Flagellin-deficient outer membrane vesicles as adjuvant induce cross-protection of Salmonella Typhimurium outer membrane proteins against infection by heterologous Salmonella serotypes [J] . Liu Qiong, Tan Kuang, Yuan Jianhui, International journal of medical microbiology: IJMM . 2018,第7期

机译：鞭毛蛋白缺乏的外膜囊泡作为佐剂诱导异膜血管膜蛋白的交叉保护免受异源沙门氏菌血清型的感染
3. Immunogenicity and Cross-Protective Efficacy Induced by Outer Membrane Proteins from Salmonella Typhimurium Mutants with Truncated LPS in Mice [J] . Qiong Liu, Qing Liu, Xinxin Zhao, International Journal of Molecular Sciences . 2016,第3期

机译：截短LPS鼠伤寒沙门氏菌突变体的外膜蛋白诱导的免疫原性和交叉防护功效。
4. Alterations induced by transition metals nickel, cadmium and mercury in Salmonella typhimurium growth and membrane proteins [C] . Hossein Tayefi-Nasrabadi, Ezzatollah Keyhani International Conference on Environmental, Industrial and Applied Microbiology . 2009

机译：过渡金属镍，镉和汞在沙门氏菌生长和膜蛋白中诱导的改变
5. STRUCTURAL AND FUNCTIONAL INTERACTIONS OF ISOPRENOL-PHOSPHATE ASSOCIATED GLYCOSYL-TRANSFERASE ENZYMES IN THE SYNTHESIS OF THE SALMONELLA TYPHIMURIUM OUTER MEMBRANE. [D] . RUNDELL, MARY KATHLEEN. 1973

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6. Protective immunity induced by outer membrane proteins of Salmonella typhimurium in mice. [O] . V Udhayakumar, V R Muthukkaruppan 1987

机译：鼠伤寒沙门氏菌外膜蛋白诱导的小鼠保护性免疫。
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Protective immunity induced by outer membrane proteins of Salmonella typhimurium in mice.

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