Haemophilus ducreyi hemolysin acts as a contact cytotoxin and damages human foreskin fibroblasts in cell culture.

M J Alfa; P DeGagne; P A Totten

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Haemophilus ducreyi hemolysin acts as a contact cytotoxin and damages human foreskin fibroblasts in cell culture.

机译：杜克雷嗜血杆菌溶血素作为一种接触性细胞毒素，在细胞培养中会破坏人的包皮成纤维细胞。

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Haemophilus ducreyi, which causes the sexually transmitted disease chancroid, produces several factors that damage human cells. We used isogenic mutants of H. ducreyi 35000 to demonstrate that the hemolytic activity and the cytotoxic effect of H. ducreyi on human foreskin fibroblasts are due to the same toxin.

机译：杜克伊嗜血杆菌（Haemophilus ducreyi）会导致性传播疾病类c虫，会产生多种破坏人体细胞的因子。我们使用H. ducreyi 35000的同基因突变体来证明H. ducreyi对人类包皮成纤维细胞的溶血活性和细胞毒性作用是由于相同的毒素引起的。

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《Infection and immunity》 |1996年第6期|共4页
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M J Alfa; P DeGagne; P A Totten;
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中图分类医学免疫学;
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1. Haemophilus ducreyi adheres to but does not invade cultured human foreskin cells. [J] . M J Alfa, P Degagne, T Hollyer Infection and immunity . 1993,第5期

机译：杜克伊嗜血杆菌粘附但不侵袭培养的人包皮细胞。
2. Extracellular matrix isolated from foreskin fibroblasts supports long-term xeno-free human embryonic stem cell culture. [J] . Meng G, Liu S, Li X, Stem cells and development . 2010,第4期

机译：从包皮成纤维细胞分离的细胞外基质支持长期无异种人类胚胎干细胞培养。
3. Expression of Cytolethal Distending Toxin and Hemolysin Is Not Required for Pustule Formation by Haemophilus ducreyi in Human Volunteers [J] . Royden S. Young, Kate R. Fortney, Valentina Gelfanova, Infection and immunity . 2001,第3期

机译：杜克嗜血杆菌在人类志愿者中形成脓疱并不需要表达细胞死亡的毒素和溶血素。
4. Multi-layered films of self-assembled capillary alginate hydrogel (Capgel™) induces preferential orientation of human foreskin fibroblasts [C] . Kwan MWC, Wheeless C, Mathews M, Society for Biomaterials annual meeting and exposition . 2019

机译：自组装毛细管藻酸盐水凝胶（Capgel™）的多层膜诱导人包皮成纤维细胞的优先取向
5. Phosphoethanolamine transferases in Haemophilus ducreyi modify lipid A and contribute to human defensin resistance. [D] . Trombley, Michael Patrick. 2015

机译：杜克氏嗜血杆菌中的磷酸乙醇胺转移酶修饰脂质A，并增强了人类对防御素的抵抗力。
6. Haemophilus ducreyi hemolysin acts as a contact cytotoxin and damages human foreskin fibroblasts in cell culture. [O] . M J Alfa, P DeGagne, P A Totten 1996

机译：杜克雷嗜血杆菌溶血素作为一种接触性细胞毒素在细胞培养中会损害人的包皮成纤维细胞。
7. Haemophilus ducreyi adheres to but does not invade cultured human foreskin cells [O] . M J Alfa, P Degagne, T Hollyer 1993

机译：嗜血杆菌Ducreyi坚持但没有侵犯培养的人类包皮细胞
8. Benzo(a)pyrene Diol Epoxide DNA Adduct Formation in Transformable and Non-Transformable Human Foreskin Fibroblast Cells in Vitro. [R] . Tejwani, R., Jeffrey, A. M., Milo, G. E. 1981

机译：苯并（a）芘二醇环氧化物DNa加合物在可转化和不可转化的人类包皮成纤维细胞体外形成。

Haemophilus ducreyi hemolysin acts as a contact cytotoxin and damages human foreskin fibroblasts in cell culture.

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