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Identification of an Insertion Sequence Located in a Region Encoding Virulence Factors of Streptococcus pyogenes

机译:位于编码化脓性链球菌致病因子的区域中的插入序列的鉴定。

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An insertion sequence, IS1562, was identified in aStreptococcus pyogenes strain of the clinically important M1 serotype. IS1562 is located in the mgaregulon between the genes coding for the M protein and the C5a peptidase, both important virulence factors. The same or similar insertion sequences were found in most S. pyogenes strains, but the chromosomal location differed among isolates.
机译:在临床上具有重要意义的M1血清型的化脓性链球菌菌株中鉴定出插入序列IS 1562 。 IS 1562 位于 mga 调节子之间,M编码基因和C5a肽酶都是重要的毒力因子。在大多数 S中发现了相同或相似的插入序列。化脓菌菌株,但分离株的染色体位置不同。

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