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首页> 外文期刊>Infection and immunity >Measurement of streptococcal cell wall in tissues of rats resistant or susceptible to cell wall-induced chronic erosive arthritis.
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Measurement of streptococcal cell wall in tissues of rats resistant or susceptible to cell wall-induced chronic erosive arthritis.

机译:在对细胞壁诱导的慢性糜烂性关节炎有抗性或易感性的大鼠组织中,链球菌细胞壁的测量。

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The quantity of streptococcal cell wall localized in the joints of rats of strains which are either susceptible (Sprague-Dawley, LEW/N, M520/N) or resistant (Buffalo, WKY/N, F344/N) to cell wall-induced chronic erosive arthritis was measured after intraperitoneal injection of group A streptococcal cell wall fragments. Susceptibility or resistance was not associated with a difference in the amount of cell wall localized in limbs or other tissues. It is concluded that although localization of cell wall in joint tissue is essential for development of arthritis, the relative resistance of certain rat strains reflects genetic regulation of inflammatory response rather than a quantitative difference in localization of cell wall in joints.
机译:链球菌细胞壁的数量位于大鼠的关节中,它们对细胞壁诱导的慢性病易感(Sprague-Dawley,LEW / N,M520 / N)或耐药(Buffalo,WKY / N,F344 / N)在腹膜内注射A组链球菌细胞壁碎片后,测量糜烂性关节炎。敏感性或抵抗力与肢体或其他组织中定位的细胞壁数量的差异无关。结论是,尽管关节组织中细胞壁的定位对于关节炎的发展是必不可少的,但某些大鼠品系的相对抗性反映了炎症反应的遗传调控,而不是关节中细胞壁定位的定量差异。

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