Induction of interleukin (IL)-1beta and IL-8 mRNA expression in porcine macrophages by lipopolysaccharide from Serpulina hyodysenteriae.

R E Sacco; S K Nibbelink; M J Baarsch; M P Murtaugh; M J Wannemuehler

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Induction of interleukin (IL)-1beta and IL-8 mRNA expression in porcine macrophages by lipopolysaccharide from Serpulina hyodysenteriae.

机译：猪痢疾螺旋体脂多糖诱导猪巨噬细胞中白介素（IL）-1β和IL-8 mRNA表达。

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Lipopolysaccharide (LPS) is a classic inducer of inflammatory cytokines and is a key virulence factor for most gram-negative pathogens. The effect of phenol-water (LPS) and butanol-water (endotoxin) extracts from Serpulina hyodysenteriae on inflammatory cytokine mRNA expression from porcine alveolar macrophages was investigated. The LPS and endotoxin extracts from S. hyodysenteriae induced a dose-dependent expression of interleukin 1beta (IL-1beta) and IL-8 which was weak compared with the responses induced by Escherichia coli LPS. In addition, the spirochetal extracts induced no detectable upregulation of mRNA expression for either IL-6 or tumor necrosis factor alpha.

机译：脂多糖（LPS）是炎性细胞因子的经典诱导剂，并且是大多数革兰氏阴性病原体的关键毒力因子。研究了猪痢疾螺旋体中酚水（LPS）和丁醇水（内毒素）提取物对猪肺泡巨噬细胞炎性细胞因子mRNA表达的影响。猪痢疾链球菌的LPS和内毒素提取物诱导白介素1beta（IL-1beta）和IL-8的剂量依赖性表达，与大肠杆菌LPS诱导的反应相比，该表达较弱。此外，螺旋提取物没有诱导IL-6或肿瘤坏死因子α的mRNA表达上调。

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《Infection and immunity》 |1996年第10期|共4页
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R E Sacco; S K Nibbelink; M J Baarsch; M P Murtaugh; M J Wannemuehler;
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中图分类医学免疫学;
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1. Induction of interleukin (IL)-1beta and IL-8 mRNA expression in porcine macrophages by lipopolysaccharide from Serpulina hyodysenteriae. [J] . R E Sacco, S K Nibbelink, M J Baarsch, Infection and immunity . 1996,第10期

机译：猪痢疾螺旋体脂多糖诱导猪巨噬细胞中白介素（IL）-1β和IL-8 mRNA表达。
2. Induction of interleukin (IL)-1beta, IL-10, IL-8 and immunoglobulin G by Porphyromonas gingivalis HmuY in humans. [J] . Trindade SC, Olczak T, Gomes Filho IS, Journal of periodontal research . 2012,第1期

机译：牙龈卟啉单胞菌HmuY在人中诱导白介素（IL）-1β，IL-10，IL-8和免疫球蛋白G。
3. Enhanced gastric IL-18 mRNA expression in Helicobacter pylori-infected children is associated with macrophage infiltration, IL-8, and IL-1 beta mRNA expression. [J] . Dzierzanowska-Fangrat K, Michalkiewicz J, Cielecka-Kuszyk J, European journal of gastroenterology and hepatology . 2008,第4期

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4. Relationship between Expression of IL-8 mRNA in Peripheral Blood and Women with Endometriosis [C] . SUN Lin, WANG Jian, GAO Ke-fa, 2009 IEEE International Symposium on IT in Medicine Education( IEEE 教育与医药信息化国际会议）论文集 . 2009

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机译：IGF-1介导卵巢癌细胞中IL-8基因表达的转录后调控：mRNA结合蛋白HuR的作用。
6. Induction of interleukin (IL)-1beta and IL-8 mRNA expression in porcine macrophages by lipopolysaccharide from Serpulina hyodysenteriae. [O] . R E Sacco, S K Nibbelink, M J Baarsch, 1996

机译：猪痢疾螺旋体脂多糖诱导猪巨噬细胞中白介素（IL）-1β和IL-8 mRNA表达。
7. Induction of interleukin (IL)-1beta and IL-8 mRNA expression in porcine macrophages by lipopolysaccharide from Serpulina hyodysenteriae [O] . R E Sacco, S K Nibbelink, M J Baarsch, 1996

机译：来自Serpulina Hyodysenteriae的脂多糖中白细胞介素（IL）-1Beta和IL-8 mRNA表达的诱导
8. Cytokine (Tumor Necrosis Factor, IL-6, and IL-8) Production by Respiratory Syncytial Virus-Infected Human Alveolar Macrophages [R] . Becker, S., Quay, J., Soukup, J. 1991

机译：呼吸道合胞病毒感染的人肺泡巨噬细胞产生细胞因子（肿瘤坏死因子，IL-6和IL-8）

Induction of interleukin (IL)-1beta and IL-8 mRNA expression in porcine macrophages by lipopolysaccharide from Serpulina hyodysenteriae.

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