Infection of macrophage-like cells by Legionella species that have not been associated with disease.

W A OConnell; L Dhand; N P Cianciotto

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Infection of macrophage-like cells by Legionella species that have not been associated with disease.

机译：与疾病无关的军团菌感染巨噬细胞样细胞。

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We assessed the ability of Legionella species that have not been associated with disease to infect macrophage-like U937 cells. Two of fourteen species tested exhibited a 50% infective dose that was within I log unit of that of virulent L. pneumophila. Indeed, intracellular CFU of L. jamestowniensis and L. parisiensis increased 100-fold over a 72-h period. These data indicate that additional legionellae can flourish within phagocytes and therefore, can, if given the opportunity, cause disease.

机译：我们评估了与疾病无关的军团菌感染巨噬细胞样U937细胞的能力。测试的14个物种中，有两个物种表现出50％的感染剂量，该剂量在有毒的肺炎乳杆菌的I log单位内。的确，在72小时的时间内，詹姆士L. jamestowniensis和帕里斯L. parisiensis的细胞内CFU增加了100倍。这些数据表明，另外的军团菌可以在吞噬细胞中生长，因此，如果有机会，可以引起疾病。

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《Infection and immunity》 |1996年第10期|共4页
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W A OConnell; L Dhand; N P Cianciotto;
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中图分类医学免疫学;
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1. Infection of macrophage-like cells by Legionella species that have not been associated with disease. [J] . W A OConnell, L Dhand, N P Cianciotto Infection and immunity . 1996,第10期

机译：与疾病无关的军团菌感染巨噬细胞样细胞。
2. Evidence for apoptosis of human macrophage-like HL-60 cells by Legionella pneumophila infection. [J] . A Müller, J Hacker, B C Brand Infection and immunity . 1996,第12期

机译：嗜肺军团杆菌感染可导致人巨噬细胞样HL-60细胞凋亡的证据。
3. Difference in Legionella pneumophila growth permissiveness between J774.1 murine macrophage-like JA-4 cells and lipopolysaccharide (LPS)-resistant mutant cells, LPS1916, after stimulation with LPS. [J] . F Kura, K Suzuki, H Watanabe, Infection and immunity . 1994,第12期

机译：用LPS刺激后，J774.1鼠巨噬细胞样JA-4细胞与抗脂多糖（LPS）的突变细胞LPS1916之间的嗜肺军团菌生长许可性有所不同。
4. Morphological varieties of microcolonies of legionella species grown in vero cells [C] . Midori Ogawa, Akemi Takade, Hatsumi Taniguchi, 7th China-Japan International Congress of Microbiology Shanghai Symposium-2000 4-6 August 2000 Shanghai . 2000

机译：Vero细胞中生长的军团菌种微殖民地的形态学变种
5. Complementary immune roles for infected and uninfected cells during Legionella pneumophila infection. [D] . Copenhaver, Alan M. 2015

机译：嗜肺军团菌感染期间感染和未感染细胞的互补免疫作用。
6. Infection of macrophage-like cells by Legionella species that have not been associated with disease. [O] . W A OConnell, L Dhand, N P Cianciotto 1996

机译：与疾病无关的军团菌感染巨噬细胞样细胞。
7. Infection of macrophage-like cells by Legionella species that have not been associated with disease [O] . W A OConnell, L Dhand, N P Cianciotto 1996

机译：通过与疾病无关的军团菌物种感染巨噬细胞样细胞

Infection of macrophage-like cells by Legionella species that have not been associated with disease.

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