S-Fimbria-Encoding Determinant sfa I Is Located on Pathogenicity Island III536 of UropathogenicEscherichia coli Strain 536

Ulrich Dobrindt; Gabriele Blum-Oehler; Thomas Hartsch; Gerhard Gottschalk; Eliora Z. Ron; Reinhard Fünfstück; J?rg Hacker

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S-Fimbria-Encoding Determinant sfa I Is Located on Pathogenicity Island III536 of UropathogenicEscherichia coli Strain 536

机译：编码S-菌落的决定因子sfa I位于致病性大肠杆菌菌株536的致病性岛III536上

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The sfa _I determinant encoding the S-fimbrial adhesin of uropathogenic Escherichia colistrains was found to be located on a pathogenicity island of uropathogenic E. coli strain 536. This pathogenicity island, designated PAI III₅₃₆, is located at 5.6 min of theE. coli chromosome and covers a region of at least 37 kb between the tRNA locus thrW and yagU. As far as it has been determined, PAI III₅₃₆ also contains genes which code for components of a putative enterochelin siderophore system of E. coli and Salmonella spp. as well as for colicin V immunity. Several intact or nonfunctional mobility genes of bacteriophages and insertion sequence elements such as transposases and integrases are present on PAI III₅₃₆. The presence of known PAI III₅₃₆ sequences has been investigated in several wild-type E. coli isolates. The results demonstrate that the determinants of the members of the S-family of fimbrial adhesins may be located on a common pathogenicity island which, in E. coli strain 536, replaces a 40-kb DNA region which represents anE. coli K-12-specific genomic island.

机译：发现编码尿路致病性大肠杆菌菌株S纤维粘附素的 sfa _{I 决定簇位于尿路致病性的致病岛上E．大肠杆菌536菌株。该致病岛称为PAI III _{536 ，位于E E的5.6分钟处。大肠埃希菌染色体，并在tRNA基因座 thrW 和 yagU 之间至少覆盖了37 kb的区域。据确定，PAI III _{536 还包含编码假定的Eem肠螯合铁载体系统组分的基因。大肠杆菌和沙门氏菌 spp。以及针对大肠菌素V的免疫力。 PAI III _{536 上存在几个完整的或非功能性的噬菌体迁移基因和转座酶和整合酶等插入序列元件。已经在几种野生型 E中研究了已知的PAI III _{536 序列的存在。大肠杆菌分离株。结果表明，纤维黏附素S家族成员的决定因素可能位于 E中的共同致病岛上。大肠杆菌536菌株替换了代表 E的40 kb DNA区域。大肠杆菌K-12特异的基因岛。}}}}} 展开▼

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《Infection and immunity》 |2001年第7期|共9页

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Ulrich Dobrindt; Gabriele Blum-Oehler; Thomas Hartsch; Gerhard Gottschalk; Eliora Z. Ron; Reinhard Fünfstück; J?rg Hacker;
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1. S-Fimbria-Encoding Determinant sfa I Is Located on Pathogenicity Island III536 of UropathogenicEscherichia coli Strain 536 [J] . Ulrich Dobrindt, Gabriele Blum-Oehler, Thomas Hartsch, Infection and immunity . 2001,第7期

机译：编码S-菌落的决定因子sfa I位于致病性大肠杆菌菌株536的致病性岛III536上

2. Identification of novel DNA sequence associated with pathogenicity island III536 locus in Uropathogenic Escherichia coli isolate and distribution of virulence determinants in beta-lactam resistant isolates [J] . Bin Thani Ali Salman Microbial Pathogenesis . 2018,第期

机译：鉴定与致病药尿道尿素尿嘧啶III536基因座相关的新型DNA序列分离β-内酰胺分离株中的毒力决定因素分布

3. The Pathogenicity Island-Associated K15 Capsule Determinant Exhibits a Novel Genetic Structure and Correlates with Virulence in Uropathogenic Escherichia coli Strain 536 [J] . Gy?rgy Schneider, Ulrich Dobrindt, Holger Brüggemann, Infection and immunity . 2004,第10期

机译：致病性岛相关的K15胶囊行列式展示了一种新的遗传结构，并与致病性大肠杆菌菌株536中的毒力相关。

4. CHALLENGE WITH PATHOGENIC STRAINS OF E. COLI AT WEANING. I. CLINICAL SIGNS AND REISOLATION OF CHALLENGE STRAINS [C] . L. Melin, S. Mattsson, P. Wallgren Congress of the International Pig Veterinary Society . 2000

机译：断奶大肠杆菌致病菌株挑战。 I.临床迹象和挑战菌株的重新辨

5. Identification of genomic differences between Escherichia coli strains pathogenic for poultry and E. coli K-12 MG1655. [D] . Stocki, Stacy Lynn. 2003

机译：鉴定家禽致病性大肠杆菌菌株与大肠杆菌K-12 MG1655之间的基因组差异。

6. S-Fimbria-Encoding Determinant sfaI Is Located on Pathogenicity Island III536 of Uropathogenic Escherichia coli Strain 536 [O] . Ulrich Dobrindt, Gabriele Blum-Oehler, Thomas Hartsch, 2001

机译：编码S-菌毛的决定簇sfaI位于尿毒原性大肠杆菌菌株536的致病性岛III536上

7. S-Fimbria-Encoding Determinant sfaI Is Located on Pathogenicity Island III536 of Uropathogenic Escherichia coli Strain 536 [O] . Dobrindt, Ulrich, Blum-Oehler, Gabriele, Hartsch, Thomas, 2001

机译：编码S-菌落的决定簇sfaI位于致病性大肠杆菌菌株536的致病性岛III536上

1. 后期酰基转移酶编码基因lpxL对禽致病性大肠杆菌菌株E058致病性的影响 [J] . 许慧卿 ,高璐 ,穆晓惠 . 畜牧兽医学报 . 2016,第009期

2. 禽致病性大肠杆菌O2:K1菌株IMT5155基因组特征及DE205B株黏附素和转录因子的功能研究 [A] . 诸葛祥凯 . 2016

1. Recombinant DNA pG4223 and pG14223, recombinant plasmid DNA pQE 30-pG4223 and pQE 30-pG14223, providing for the G4223 and G14223 polypeptides, strains of Esherichia coli M 15-G4223 and Esherichia coli M 15-G14223, transfaccinated strains M 15-G4223 and Esherichia coli M 15-G14223; pQE 30-pG14223, expressing recombinant G4223 and G14223 polypeptides, recombinant G4223 and G14223 polypeptides, with the ability to selectively bind IgG and their use as ligands in affinity chromatography for isolating IgG from blood serum [P] . 外国专利： RU2017146174A . 2019-06-27

机译：重组DNA pG4223和pG14223，重组质粒DNA pQE 30-pG4223和pQE 30-pG14223，提供G4223和G14223多肽，大肠杆菌M 15-G4223和大肠杆菌M 15-G14223菌株，转接种的菌株M 15-G4223和大肠杆菌M 15-G14223;表达重组G4223和G14223多肽，重组G4223和G14223多肽的pQE 30-pG14223，具有选择性结合IgG的能力及其在亲和层析中从血清中分离IgG的配体用途

2. ATTENUATED SALMONELLA VARIANT STRAIN RESULTING FROM THE GENETIC TRANSFORMATION OF ADHESIN FROM PATHOGENIC PIG ESCHERICHIA COLI AND A VACCINE COMPOSITION COMPRISING THE SAME FOR PREVENTING AND TREATING PATHOGENIC COLIBACILLOSIS AND SALMONELLOSIS IN PIGS [P] . 外国专利： WO2011025310A2 . 2011-03-03

机译：致病性猪>埃希氏菌和包含其的疫苗组合物的遗传转化所导致的减弱的沙门氏菌变异株

3. ATTENUATED SALMONELLA VARIANT STRAIN RESULTING FROM THE GENETIC TRANSFORMATION OF ADHESIN FROM PATHOGENIC PIG ESCHERICHIA COLI AND A VACCINE COMPOSITION COMPRISING THE SAME FOR PREVENTING AND TREATING PATHOGENIC COLIBACILLOSIS AND SALMONELLOSIS IN PIGS [P] . 外国专利： WO2011025310A9 . 2011-07-28

机译：致病性猪>埃希氏菌和包含其的疫苗组合物的遗传转化所导致的减弱的沙门氏菌变异株

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S-Fimbria-Encoding Determinant sfa I Is Located on Pathogenicity Island III536 of UropathogenicEscherichia coli Strain 536

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