Successive synovial Mycoplasma hominis isolates exhibit apparent antigenic variation.

L D Olson; C A Renshaw; S W Shane; M F Barile

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Successive synovial Mycoplasma hominis isolates exhibit apparent antigenic variation.

机译：连续的滑膜人型支原体分离株表现出明显的抗原变异。

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The expression of surface proteins by 14 successive Mycoplasma hominis isolates obtained from the synovial fluid of a chronically infected septic arthritis patient was examined. Marked differences in the expression of surface proteins, as determined by monoclonal antibodies raised against the first isolate, were observed. However, identical restriction patterns and virtually identical hybridization patterns with probes containing the conserved genes of the Mycoplasma capricolum rRNA operon and the Escherichia coli elongation factor Tu suggest that the protein differences might reflect antigenic variation by M. hominis during infection.

机译：检查了从慢性感染的化脓性关节炎患者的滑液中获得的14个连续的人支原体支原体分离株表面蛋白的表达。观察到表面蛋白表达的明显差异，这是由针对第一个分离株的单克隆抗体确定的。但是，相同的限制性酶切模式和实际上与包含含有支原体rRNA操纵子和大肠杆菌延伸因子Tu的保守基因的探针的杂交模式相同，表明该蛋白差异可能反映了人型分枝杆菌在感染过程中的抗原变异。

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《Infection and immunity》 |1991年第9期|共3页
作者
L D Olson; C A Renshaw; S W Shane; M F Barile;
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中图分类医学免疫学;
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6. Successive synovial Mycoplasma hominis isolates exhibit apparent antigenic variation. [O] . L D Olson, C A Renshaw, S W Shane, 1991

机译：连续滑膜人型支原体分离株表现出明显的抗原变异。
7. Antigenic and genomic homogeneity of successive Mycoplasma hominis isolates [O] . Jensen, Lise T., Thorsen, P., Møller, B., 1998

机译：连续人型支原体分离株的抗原和基因组同质性

Successive synovial Mycoplasma hominis isolates exhibit apparent antigenic variation.

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