Plasmodium falciparum Parasites Expressing Pregnancy-Specific Variant Surface Antigens Adhere Strongly to the Choriocarcinoma Cell Line BeWo

Rikke N. Haase; Rosette Megnekou; Maja Lundquist; Michael F. Ofori; Lars Hviid; Trine Staalsoe

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Plasmodium falciparum Parasites Expressing Pregnancy-Specific Variant Surface Antigens Adhere Strongly to the Choriocarcinoma Cell Line BeWo

机译：表达妊娠特定变体表面抗原的恶性疟原虫寄生虫强烈粘附于绒毛膜癌细胞系。

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Placenta-sequestering Plasmodium falciparum parasites causing pregnancy-associated malaria express pregnancy-specific variant surface antigens (VSA_PAM). We report here that VSA_PAM-expressing patient isolates adhere strongly to the choriocarcinoma cell line BeWo and that the BeWo line can be used to efficiently select for VSA_PAM expression in vitro.

机译：导致与妊娠相关的疟疾的胎盘隔离型恶性疟原虫表达了妊娠特异性变体表面抗原（VSA _{PAM ）。我们在这里报告说，表达VSA _{PAM 的患者分离株强烈粘附于绒癌细胞系BeWo，并且BeWo系可用于有效选择体外VSA _{PAM 表达。}}}

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《Infection and immunity》 |2006年第5期|共4页
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Rikke N. Haase; Rosette Megnekou; Maja Lundquist; Michael F. Ofori; Lars Hviid; Trine Staalsoe;
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1. Antibodies to Escherichia coli-Expressed C-Terminal Domains of Plasmodium falciparum Variant Surface Antigen 2-Chondroitin Sulfate A (VAR2CSA) Inhibit Binding of CSA-Adherent Parasites to Placental Tissue [J] . Tracy Saveria, Andrew V. Oleinikov, Kathryn Wiliamson, Infection and immunity . 2013,第4期

机译：恶性疟原虫变体表面抗原2-硫酸软骨素A（VAR2CSA）的大肠杆菌表达的C末端域的抗体抑制CSA粘附的寄生虫与胎盘组织的结合。
2. Variants of Plasmodium falciparum erythrocyte membrane protein 1 expressed by different placental parasites are closely related and adhere to chondroitin sulfate A. [J] . Khattab A, Kun J, Deloron P, The Journal of Infectious Diseases . 2001,第7期

机译：不同胎盘寄生虫表达的恶性疟原虫红细胞膜蛋白1的变异密切相关，并粘附于硫酸软骨素A。
3. Effect of cytokine treatment on the in vitro expression of the P. falciparum adhesion receptor chondroitin-4-sulphate on the surface of human choriocarcinoma (BeWo) cells [J] . Yvonne Adams, Reinhard Schwartz-Albiez, James S. McCarthy, Parasitology Research . 2007,第2期

机译：细胞因子处理对人绒毛膜癌细胞（BeWo）表面恶性疟原虫粘附受体4-硫酸软骨素的体外表达的影响
4. Just-in-time expression of influential genes in the cellular networks of the malaria parasite Plasmodium falciparum during the red blood cycle [C] . Xinran Yu, Hao Zhang, Timothy G. Lilburn, IEEE International Conference on Bioinformatics and Biomedicine . 2016

机译：疟疾寄生虫恶性疟原虫红细胞周期内细胞网络中影响基因的及时表达
5. The identification of novel variant surface antigens of Plasmodium falciparum. [D] . Lukens, Amanda Kathleen. 2011

机译：恶性疟原虫的新型变异表面抗原的鉴定。
6. Plasmodium falciparum Parasites Expressing Pregnancy-Specific Variant Surface Antigens Adhere Strongly to the Choriocarcinoma Cell Line BeWo [O] . Rikke N. Haase, Rosette Megnekou, Maja Lundquist, 2006

机译：表达妊娠特定变异表面抗原的恶性疟原虫寄生虫强烈粘附于绒毛膜癌细胞系BeWo
7. Plasmodium falciparum Parasites Expressing Pregnancy-Specific Variant Surface Antigens Adhere Strongly to the Choriocarcinoma Cell Line BeWo [O] . Haase, Rikke N., Megnekou, Rosette, Lundquist, Maja, 2006

机译：表达妊娠特定变异表面抗原的恶性疟原虫寄生虫强烈粘附于绒毛膜癌细胞系BeWo

Plasmodium falciparum Parasites Expressing Pregnancy-Specific Variant Surface Antigens Adhere Strongly to the Choriocarcinoma Cell Line BeWo

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