Alpha-Toxin of Clostridium perfringens Is Not an Essential Virulence Factor in Necrotic Enteritis in Chickens

Anthony?L.? Keyburn; Scott A. Sheedy; Mark E. Ford; Mark M. Williamson; Milena M. Awad; Julian I. Rood; Robert J. Moore

首页> 外文期刊>Infection and immunity >Alpha-Toxin of Clostridium perfringens Is Not an Essential Virulence Factor in Necrotic Enteritis in Chickens

【24h】

Alpha-Toxin of Clostridium perfringens Is Not an Essential Virulence Factor in Necrotic Enteritis in Chickens

机译：产气荚膜梭菌的α-毒素不是鸡坏死性肠炎的必需毒力因子

获取原文

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

The Clostridium perfringens alpha-toxin has previously been implicated as the major virulence factor in necrotic enteritis in chickens, although definitive proof has not been reported. In this study an alpha-toxin mutant was constructed in a virulent chicken isolate and shown to retain full virulence in a chicken disease model. These results demonstrated that alpha-toxin is not an essential virulence factor in the pathogenesis of necrotic enteritis in chickens.

机译：尽管没有确切证据证明，产气荚膜梭菌α-毒素曾被认为是鸡坏死性肠炎的主要致病因子。在这项研究中，在有毒的鸡隔离株中构建了α-毒素突变体，并显示在鸡疾病模型中保留了全部毒力。这些结果证明α-毒素不是鸡坏死性肠炎发病机理中的必需毒力因子。 展开▼

著录项

来源
《Infection and immunity》 |2006年第11期|共5页

作者
Anthony?L.? Keyburn; Scott A. Sheedy; Mark E. Ford; Mark M. Williamson; Milena M. Awad; Julian I. Rood; Robert J. Moore;
展开▼

作者单位

展开▼

收录信息

原文格式 PDF

正文语种

中图分类医学免疫学;

关键词

相似文献

外文文献

中文文献

专利

1. Quantification of Cell Proliferation and Alpha-Toxin Gene Expression of Clostridium perfringens in the Development of Necrotic Enteritis in Broiler Chickens [J] . Weiduo Si, Joshua Gong, Yanming Han, Applied and Environmental Microbiology . 2007,第21期

机译：肉鸡坏死性肠炎发生过程中产气荚膜梭菌细胞增殖和α-毒素基因表达的定量

2. Necrotic enteritis locus 1 diguanylate cyclase and phosphodiesterase (cyclic-di-GMP) gene mutation attenuates virulence in an avian necrotic enteritis isolate of ce:italic>Clostridium perfringens/ce:italic> [J] . Veterinary Microbiology . 2017,第期

机译：坏死肠炎基因座1达瓜酸盐环化酶和磷酸二酯酶（环状二-MMP）基因突变在禽死性肠炎中衰减毒力且斜体>梭菌酸纤维素＆ / ce：斜体>

3. Associated profiles of virulence gene markers in Clostridium perfringens strains isolated from healthy and diseased broiler chickens with necrotic enteritis. [J] . Mohamed M. A., Ahmed S. O., Motelib T. Y. A. Assiut Veterinary Medical Journal . 2009,第123期

机译：从健康和患病坏死性肠炎的肉鸡分离出的产气荚膜梭状芽胞杆菌菌株中毒力基因标记的相关图谱。

4. INVESTIGATIONS INTO THE SYNERGIC EFFECT OF POSTNATAL EXPERIMENTAL INFECTION WITH ISOSPORA SUIS AND NATURAL INFECTION WITH CLOSTRIDIUM PERFRINGENS J32 FOR THE DEVELOPMENT OF NECROTIC ENTERITIS IN PIGLE [C] . H.-C. Mundt, M. Krttger, B. Westphal, Congress of the International Pig Veterinary Society . 2008

机译：对产后试验型和梭菌梭菌J32对梭菌J32的自然感染的协同作用的调查

5. The importance of the strain of Clostridium perfringens in the development of necrotic enteritis of poultry. [D] . Martin, Thomas G. 2010

机译：产气荚膜梭菌菌株在家禽坏死性肠炎发展中的重要性。

6. Alpha-Toxin of Clostridium perfringens Is Not an Essential Virulence Factor in Necrotic Enteritis in Chickens [O] . Anthony L. Keyburn, Scott A. Sheedy, Mark E. Ford, 2006

机译：产气荚膜梭菌的α-毒素不是鸡坏死性肠炎的必需毒力因子

7. Alpha-Toxin of Clostridium perfringens Is Not an Essential Virulence Factor in Necrotic Enteritis in Chickens▿ [O] . Keyburn, Anthony L. , Sheedy, Scott A., Ford, Mark E., 2006

机译：产气荚膜梭菌α毒素不是鸡坏死性肠炎的必需毒力因子▿

1. 仔猪产气荚膜梭菌肠毒血症病原诊断及疫苗研究Ⅲ.7株A型产气荚膜梭菌菌株的产毒素试验 [J] . 屠伟英 ,蒋玉文 ,蔡祈英 . 中国兽药杂志 . 2003,第008期

2. 产气荚膜梭菌次要毒力因子的研究进展 [J] . 田冬青 ,蒋玉文 ,杨京岚 . 畜牧与饲料科学 . 2010,第010期

3. 产气荚膜梭菌主要毒力因子的分子生物学研究进展 [J] . 宋厚辉 ,方维焕 ,周继勇 . 畜牧兽医科技信息 . 2001,第001期

4. 产气荚膜梭菌主要毒力因子的分子生物学研究进展 [J] . 宋厚辉 ,方维焕 ,等 . 预防兽医学进展 . 2001,第002期

5. 腐败梭菌α毒素和产气荚膜梭菌ε毒素的共表达及其免疫效力评价 [J] . 彭国瑞 ,彭小兵 ,李旭妮 . 中国兽药杂志 . 2019,第002期

6. 抗产气荚膜梭菌β毒素IgG的纯化与β毒素Dot-ELISA测定方法的研究 [C] . 张存帅 ,薛民权 . 北京微生物学会青年科技创新论坛报告会 . 1999

7. 表达产气荚膜梭菌α--β2--ε--β1类毒素的重组鸡源卷曲乳杆菌构建及抗鸡坏死性肠炎免疫保护效果分析 [A] . Mohammad Zeb Khan . 2021

1. 一种鸡坏死性肠炎的A、C型产气荚膜梭菌类毒素和菌体二价两类抗原疫苗的制备方法 [P] . 中国专利： CN104623652B . 2016.08.17

2. 一种鸡坏死性肠炎的A、C型产气荚膜梭菌类毒素和菌体二价两类抗原疫苗的制备方法 [P] . 中国专利： CN104623652A . 2015-05-20

3. Inhibiting germination of clostridium perfringens spores to reduce necrotic enteritis [P] . 外国专利： US10945996B2 . 2021-03-16

机译：抑制梭菌的萌发强制性孢子，以减少坏死肠炎

4. Inhibiting Germination of Clostridium Perfringens Spores to Reduce Necrotic Enteritis [P] . 外国专利： US2021228550A1 . 2021-07-29

机译：抑制梭菌的萌发强制性孢子，以减少坏死肠炎

5. Inhibiting Germination of Clostridium Perfringens Spores to Reduce Necrotic Enteritis [P] . 外国专利： US2019209531A1 . 2019-07-11

机译：抑制产气荚膜梭菌孢子萌发以减少坏死性肠炎

相关主题

Alpha-Toxin of Clostridium perfringens Is Not an Essential Virulence Factor in Necrotic Enteritis in Chickens

摘要

著录项

相似文献

相关主题

期刊订阅