Presence of putative sphingomyelinase genes among members of the family Leptospiraceae.

R P Segers; J A van Gestel; G J van Eys; B A van der Zeijst; W Gaastra

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Presence of putative sphingomyelinase genes among members of the family Leptospiraceae.

机译：钩端螺旋体科成员中存在推测的鞘磷脂酶基因。

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The presence of multiple DNA elements in pathogenic members of the family Leptospiraceae, similar to the sphA sphingomyelinase gene from Leptospira borgpetersenii, was demonstrated by low-stringency hybridization experiments. These DNA elements were designated putative sphingomyelinase genes. Grouping of strains by similarity of hybridization patterns corresponds to the species subdivision of the family Leptospiraceae on the basis of genetic characteristics. Therefore, hybridization with the sphA gene can be used as a taxonomic tool. These hybridization experiments indicate the presence of two groups of genetically related pathogenic Leptospira species.

机译：通过低严格性杂交实验证明，钩端螺旋体科的致病成员中存在多个DNA元素，类似于来自博氏钩端螺旋体的sphA鞘磷脂酶基因。这些DNA元件被称为推定的鞘磷脂酶基因。根据遗传特征，通过杂交模式的相似性将菌株分组对应于钩端螺旋体科的物种细分。因此，与sphA基因的杂交可用作分类学工具。这些杂交实验表明存在两组遗传相关的致病性钩端螺旋体物种。

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《Infection and immunity》 |1992年第4期|共4页
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R P Segers; J A van Gestel; G J van Eys; B A van der Zeijst; W Gaastra;
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中图分类医学免疫学;
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6. Presence of putative sphingomyelinase genes among members of the family Leptospiraceae. [O] . R P Segers, J A van Gestel, G J van Eys, 1992

机译：钩端螺旋体科成员中存在推测的鞘磷脂酶基因。
7. Transcript Analysis of Genes Encoding a Family 61 Endoglucanase and a Putative Membrane-Anchored Family 9 Glycosyl Hydrolase from Phanerochaete chrysosporium [O] . Vanden Wymelenberg, Amber, Denman, Stuart, Dietrich, Diane, 2002

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Presence of putative sphingomyelinase genes among members of the family Leptospiraceae.

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