首页> 外文期刊>Infection and immunity >Enterococcus faecalis Mutations Affecting Virulence in the Caenorhabditis elegans Model Host
【24h】

Enterococcus faecalis Mutations Affecting Virulence in the Caenorhabditis elegans Model Host

机译:粪肠球菌突变影响秀丽隐杆线虫模型宿主中的毒力。

获取原文
           

摘要

Enterococcus faecalis transposon insertion mutants were screened for attenuated killing of the nematode model host Caenorhabditis elegans. The genes disrupted in the attenuated mutants encode a variety of factors including transcriptional regulators, transporters, and damage control and repair systems. Five of nine mutants tested were attenuated in a mouse peritonitis model.
机译:筛选粪肠球菌转座子插入突变体,以减轻线虫模型宿主 em> Caenorhabditis elegans 的杀伤力。在减毒突变体中破坏的基因编码多种因子,包括转录调节因子,转运蛋白以及损伤控制和修复系统。在小鼠腹膜炎模型中,测试的9个突变体中有5个减弱了。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号