• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Infection and immunity >The Bartonella vinsonii subsp. arupensis Immunodominant Surface Antigen BrpA Gene, Encoding a 382-Kilodalton Protein Composed of Repetitive Sequences, Is a Member of a Multigene Family Conserved among Bartonella Species
【24h】

The Bartonella vinsonii subsp. arupensis Immunodominant Surface Antigen BrpA Gene, Encoding a 382-Kilodalton Protein Composed of Repetitive Sequences, Is a Member of a Multigene Family Conserved among Bartonella Species

机译：巴尔森氏菌arupensis免疫表面抗原BrpA基因，编码由重复序列组成的382-Kilodalton蛋白，是巴尔通体物种中保守的多基因家族的成员

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Bartonella proteins that elicit an antibody response during an infection are poorly defined; therefore, to characterize antigens recognized by the host, a Bartonella genomic expression library was screened with serum from an infected mouse. This process led to the discovery of a Bartonella vinsonii subsp. arupensis gene encoding a 382-kDa protein, part of a gene family encoding large proteins, each containing multiple regions of repetitive segments. The genes were termed brpA to -C (bartonella repeat protein) and bore significant similarity to genes encoding the BadA adhesin protein and members of the variably expressed outer membrane protein family of proteins from Bartonella henselae and Bartonella quintana, respectively.
机译：在感染过程中引起抗体反应的 Bartonella 蛋白定义不清;因此，为了表征宿主识别的抗原，用感染小鼠的血清筛选了 Bartonella 基因组表达文库。这一过程导致发现了 Bartonella vinsonii 亚种。编码382 kDa蛋白的 arupensis 基因，是编码大蛋白的基因家族的一部分，每个蛋白都包含多个重复片段区域。这些基因被称为 brpA 至 -C （ b 青蒿 r epeat p rotein ），并且分别与编码BadA粘附素蛋白的基因以及分别来自 Bartonella henselae 和 Bartonella quintana 的可变表达外膜蛋白家族的成员相似。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号