Th2 Responses Predominate during the Early Phases of Infection in Patients with Localized Cutaneous Leishmaniasis and Precede the Development of Th1 Responses

Eliane Bourreau; Jacques Gardon; Roger Pradinaud; Hervé Pascalis; Ghislaine Prévot-Linguet; Amina Kariminia; Launois Pascal

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Th2 Responses Predominate during the Early Phases of Infection in Patients with Localized Cutaneous Leishmaniasis and Precede the Development of Th1 Responses

机译：在局部皮肤皮肤利什曼病患者感染的早期阶段，Th2反应占主导地位，并且Th1反应发展

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Intralesional Th2 responses preceded the development of Th1 responses in localized cutaneous leishmaniasis due to Leishmania guyanensis. Although the number of parasites increased in Th2 lesions, no correlation was found between the levels of cytokine expression and the number of parasites. In contrast, the decreased number of parasites in Th1 lesions is negatively correlated to gamma interferon expression.

机译：在因Leemmania guyanensis 引起的局部皮肤利什曼病中，Th2内反应先于Th1反应的发展。尽管Th2病变中的寄生虫数量增加，但是在细胞因子表达水平和寄生虫数量之间未发现相关性。相反，Th1病变中寄生虫数量的减少与γ干扰素的表达负相关。

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《Infection and immunity》 |2003年第4期|共3页
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Eliane Bourreau; Jacques Gardon; Roger Pradinaud; Hervé Pascalis; Ghislaine Prévot-Linguet; Amina Kariminia; Launois Pascal;
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中图分类医学免疫学;
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1. Host's immune response in unresponsive and responsive patients with anthroponotic cutaneous leishmaniasis treated by meglumine antimoniate: A case-control study of Th1 and Th2 pathways [J] . Bamorovat Mehdi, Sharifi Iraj, Aflatoonian Mohammad Reza, International immunopharmacology . 2019,第期

机译：MeGlumine Antimoniate治疗的人体皮肤无射击患者无响应和响应患者的宿主免疫反应：对TH1和TH2途径的病例对照研究
2. Comparison of Th1 and Th2 Responses in Non-Healing and Healing Patients with Cutaneous Leishmaniasis [J] . Maryam Shahi, Masoud Mohajery, Seyyed Ali Akbar Shamsian, Reports of Biochemistry and Molecular Biology . 2013,第2期

机译：皮肤利什曼病的非自愈患者和自愈患者Th1和Th2反应的比较
3. Th1/Th2 immune responses are associated with active cutaneous leishmaniasis and clinical cure is associated with strong interferon-gamma production. [J] . Castellano LR, Filho DC, Argiro L Human Immunology: Official Journal of the American Society for Histocompatibility and Immunogenetics . 2009,第6期

机译：Th1 / Th2免疫反应与活跃的皮肤利什曼病有关，临床治愈与强干扰素-γ产生有关。
4. Th1/Th2/Th17 profile and T cell phenotype of an in vitro antigen presentation system in response to DC functionality, IL-2 and IGF-1 presence [C] . De Lastic A., Rodi M., Mouzaki A. International Congress of Immunology. . 2014

机译：Th1 / Th2 / Th17型概况和T细胞表型，响应于DC功能，IL-2和IGF-1存在的体外抗原呈现系统
5. APRIL (TNFSF13) in Th1, Th2, and Th17 responses. [D] . Xiao, Yanping. 2009

机译：Th1，Th2和Th17反应中的APRIL（TNFSF13）。
6. Th2 Responses Predominate during the Early Phases of Infection in Patients with Localized Cutaneous Leishmaniasis and Precede the Development of Th1 Responses [O] . Eliane Bourreau, Jacques Gardon, Roger Pradinaud, 2003

机译：在局部皮肤皮肤利什曼病患者感染的早期阶段Th2反应占主导地位并且Th1反应发展
7. Th2 Responses Predominate during the Early Phases of Infection in Patients with Localized Cutaneous Leishmaniasis and Precede the Development of Th1 Responses [O] . Bourreau, Eliane, Gardon, Jacques, Pradinaud, Roger, 2003

机译：在局部皮肤皮肤利什曼病患者感染的早期阶段，Th2反应占主导地位，并且Th1反应发展

Th2 Responses Predominate during the Early Phases of Infection in Patients with Localized Cutaneous Leishmaniasis and Precede the Development of Th1 Responses

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