Protection of Black-Tailed Prairie Dogs (Cynomys ludovicianus) against Plague after Voluntary Consumption of Baits Containing Recombinant Raccoon Poxvirus Vaccine

Jordan S. Mencher; Susan R. Smith; Tim D. Powell; Dan T. Stinchcomb; Jorge E. Osorio; Tonie E. Rocke

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Protection of Black-Tailed Prairie Dogs (Cynomys ludovicianus) against Plague after Voluntary Consumption of Baits Containing Recombinant Raccoon Poxvirus Vaccine

机译：自愿食用含有重组浣熊痘病毒疫苗的诱饵后，黑尾草原土拨鼠（Cynomys ludovicianus）免受鼠疫的保护

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Prairie dogs (Cynomys spp.) are highly susceptible to Yersinia pestis and significant reservoirs of plague for humans in the western United States. A recombinant raccoon poxvirus, expressing the F1 antigen of Y. pestis, was incorporated into a palatable bait and offered to 18 black-tailed prairie dogs (Cynomys ludovicianus) for voluntary consumption; 18 negative control animals received placebo baits. Antibody titers against Y. pestis F1 antigen increased significantly (P < 0.01) in vaccinees, and their survival was significantly higher upon challenge with Y. pestis than that of negative controls (P < 0.01).

机译：草原犬鼠（Cynomys spp。）在美国西部对鼠疫耶尔森菌和鼠疫有很高的储量。重组浣熊痘病毒，表达 Y的F1抗原。将瘟疫菌掺入可口的诱饵中，并提供给18只黑尾土拨鼠（）自愿食用; 18只阴性对照动物接受安慰剂诱饵。针对 Y的抗体效价。疫苗中的鼠疫 F1抗原显着增加（ P <0.01），并且在 Y攻击下其存活率显着提高。鼠疫（ P <0.01）。 展开▼

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《Infection and immunity》 |2004年第9期|共4页

作者
Jordan S. Mencher; Susan R. Smith; Tim D. Powell; Dan T. Stinchcomb; Jorge E. Osorio; Tonie E. Rocke;
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中图分类医学免疫学;

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1. Consumption of baits containing raccoon pox-based plague vaccines protects black-tailed prairie dogs (Cynomys ludovicianus). [J] . Rocke TE, Pussini N, Smith SR, Vector borne and zoonotic diseases . 2010,第1期

机译：食用含有痘瘟疫疫苗的诱饵可保护黑尾土拨鼠（Cynomys ludovicianus）。

2. Responses of Juvenile Black-tailed Prairie Dogs (Cynomys ludovicianus) to a Commercially Produced Oral Plague Vaccine Delivered at Two Doses [J] . Cardenas-Canales Elsa M., Wolfe Lisa L., Tripp Daniel W., Journal of wildlife diseases . 2017,第4期

机译：少年黑尾草原狗（Cynomys Ludovicianus）以两剂量递送的商业生产的口腔瘟疫疫苗的反应

3. APPARENT FIELD SAFETY OF A RACCOON POXVIRUS-VECTORED PLAGUE VACCINE IN FREE-RANGING PRAIRIE DOGS (CYNOMYS SPP.), COLORADO, USA [J] . Tripp Daniel W., Rocke Tonie E., Streich Sean P., Journal of wildlife diseases . 2015,第2期

机译：美国科罗拉多州自由放养的草原土拨鼠（CYNOMYS SPP。）上的浣熊痘病毒接种的疫苗的视场安全性

4. Prescribed fire: A proposed management tool to facilitate black-tailed prairie dog (Cynomys ludovicianus) colony expansion [C] . Felicia D Archuleta, Paulette L Ford International Grassland Congress . 2013

机译：规定的火：建议的管理工具，以促进黑尾草原狗（Cynomys Ludovicianus）殖民地扩展

5. Population genetics, fragmentation and plague in black-tailed prairie dogs (Cynomys ludovicianus). [D] . Savage, Lisa T. 2007

机译：黑尾土拨鼠（Cynomys ludovicianus）的种群遗传学，破碎和鼠疫。

6. Protection of Black-Tailed Prairie Dogs (Cynomys ludovicianus) against Plague after Voluntary Consumption of Baits Containing Recombinant Raccoon Poxvirus Vaccine [O] . Jordan S. Mencher, Susan R. Smith, Tim D. Powell, 2004

机译：自愿食用含有重组浣熊痘病毒疫苗的诱饵后黑尾草原土拨鼠（Cynomys ludovicianus）对鼠疫的防护

7. Protection of Black-Tailed Prairie Dogs (Cynomys ludovicianus) against Plague after Voluntary Consumption of Baits Containing Recombinant Raccoon Poxvirus Vaccine [O] . Mencher, Jordan S., Smith, Susan R., Powell, Tim D., 2004

机译：自愿食用含有重组浣熊痘病毒疫苗的诱饵后，黑尾草原土拨鼠（Cynomys ludovicianus）免受鼠疫的保护

1. Raccoon poxvirus recombinant vector (rrcnv) recombinant Vaccine against rabies Plasmid pfd2003 GPV - PV and methods to make the recombinant Raccoon poxvirus Vector and to induce a protective immune response against rabies [P] . 外国专利： AR066813A1 . 2009-09-16

机译：浣熊痘病毒重组载体（rrcnv）重组抗狂犬病疫苗pfd2003 GPV-PV以及制备重组浣熊痘病毒载体并诱导针对狂犬病的保护性免疫应答的方法

2. Raccoon poxvirus recombinant Vaccine for use in cats, and use of said poxvirus to prepare an effective Vaccine against feline immunodeficiency virus infection [P] . 外国专利： AR042378A2 . 2005-06-22

机译：用于猫的浣熊痘病毒重组疫苗，以及所述痘病毒用于制备抗猫免疫缺陷病毒感染的有效疫苗的用途

3. Raccoon poxvirus recombinant,Vaccine for use in cats and use of poxvirus to prepare a vaccine used to prevent or slow the disease caused by Feline immunodeficiency virus (FIV) [P] . 外国专利： AR003425A1 . 1998-08-05

机译：浣熊痘病毒重组体，用于猫的疫苗以及痘病毒用于制备预防或减缓猫免疫缺陷病毒（FIV）引起的疾病的疫苗

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Protection of Black-Tailed Prairie Dogs (Cynomys ludovicianus) against Plague after Voluntary Consumption of Baits Containing Recombinant Raccoon Poxvirus Vaccine

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