Protein Microarray for Profiling Antibody Responses to Yersinia pestis Live Vaccine

Bei Li; Lingxiao Jiang; Qifeng Song; Junxin Yang; Zeliang Chen; Zhaobiao Guo; Dongsheng Zhou; Zongmin Du; Yajun Song; Jin Wang; Hongxia Wang; Shouyi Yu; Jian Wang; Ruifu Yang

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Protein Microarray for Profiling Antibody Responses to Yersinia pestis Live Vaccine

机译：用于对鼠疫耶尔森菌活疫苗的抗体反应进行分析的蛋白质微阵列

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A protein microarray representing 149 Yersinia pestis proteins was developed to profile antibody responses in EV76-immunized rabbits. Antibodies to 50 proteins were detected. There are 11 proteins besides F1 and V antigens to which the predominant antibody response occurred, and these proteins show promise for further evaluation as candidates for subunit vaccines and/or diagnostic antigens.

机译：开发了代表149种鼠疫耶尔森菌的蛋白质微阵列，以分析经EV76免疫的兔子的抗体反应。检测到针对50种蛋白质的抗体。除F1和V抗原外，还有11种蛋白发生了主要的抗体反应，这些蛋白有望作为亚单位疫苗和/或诊断抗原的候选者进行进一步评估。

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《Infection and immunity》 |2005年第6期|共6页
作者
Bei Li; Lingxiao Jiang; Qifeng Song; Junxin Yang; Zeliang Chen; Zhaobiao Guo; Dongsheng Zhou; Zongmin Du; Yajun Song; Jin Wang; Hongxia Wang; Shouyi Yu; Jian Wang; Ruifu Yang;
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中图分类医学免疫学;
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1. Quorum sensing affects virulence-associated proteins F1, LcrV, KatY and pH6 etc of Yersinia pestis as revealed by protein microarray-based antibody profiling [J] . Chen ZL, Li B, Zhang JS, Microbes and infection . 2006,第9a10期

机译：通过基于蛋白质芯片的抗体谱分析，群体感应影响了鼠疫耶尔森氏菌的毒力相关蛋白F1，LcrV，KatY和pH6等
2. Microarray expression profiling of Yersinia pestis in response to berberine. [J] . Zhang J, Zuo G, Bai Q, Planta medica: Natural products and medicinal plant research . 2009,第4期

机译：鼠疫耶尔森氏菌对小ber碱的微阵列表达谱分析。
3. Microarray expression profiling of Yersinia pestis in response to chloramphenicol [J] . Qiu JF, Zhou DS, Qin L, FEMS Microbiology Letters . 2006,第1期

机译：氯霉素对鼠疫耶尔森氏菌的芯片表达谱分析
4. Comparative genomics of Yersinia pestis isolates and vaccine strain EV76 by whole genome microarray [C] . Peng Wang, Jianzhong Zhang, Yuanhai You, International symposium on bacterial genomics, evolution and pathogenesis. . 2010

机译：全基因组微阵列比较鼠疫耶尔森菌分离株和EV76疫苗株的基因组学
5. A novel Yersinia pestis proteome microarray for analysis of complex antibody responses. [D] . Keasey, Sarah L. 2008

机译：一种新颖的鼠疫耶尔森氏菌蛋白质组微阵列，用于分析复杂的抗体反应。
6. Protein Microarray for Profiling Antibody Responses to Yersinia pestis Live Vaccine [O] . Bei Li, Lingxiao Jiang, Qifeng Song, 2005

机译：用于对鼠疫耶尔森菌活疫苗的抗体反应进行分析的蛋白质微阵列
7. Protein Microarray for Profiling Antibody Responses to Yersinia pestis Live Vaccine [O] . Li, Bei, Jiang, Lingxiao, Song, Qifeng, 2005

机译：用于对鼠疫耶尔森菌活疫苗的抗体反应进行分析的蛋白质微阵列
8. Development of a Chemoenzymatic-like and Photoswitchable Method for the High-Through put creation of Protein Microarrays. Application to the Analysis of the Protein/Protein Interactions Involved in the YOP Virulon from Yersinia pestis [R] . Camarero, J. A. 2007

机译：用于蛋白质微阵列的高通量创建的类化学酶和光可切换方法的开发。应用于鼠疫耶尔森氏菌YOp Virulon蛋白质/蛋白质相互作用的分析

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Protein Microarray for Profiling Antibody Responses to Yersinia pestis Live Vaccine

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