首页> 外文期刊>Infection and immunity >Chlamydia trachomatis Lacks an Adaptive Response to Changes in Carbon Source Availability
【24h】

Chlamydia trachomatis Lacks an Adaptive Response to Changes in Carbon Source Availability

机译:沙眼衣原体缺乏对碳源有效性变化的适应性反应

获取原文
           

摘要

Most bacteria coordinately regulate gene expression as an adaptive response to a variety of environmental changes. One key environmental cue is the carbon source necessary for central metabolism. We used microarray analysis to monitor the global transcriptional response of the obligate intracellular pathogen Chlamydia trachomatis to the presence of glycolytic and gluconeogenic carbon sources. In contrast to free-living bacteria, changing the carbon source from glucose to glutamate or α-ketoglutarate had little effect on the global gene transcription of C. trachomatis.
机译:大多数细菌协调地调节基因表达,作为对各种环境变化的适应性反应。一种关键的环境提示是中央代谢所必需的碳源。我们使用微阵列分析来监测专性细胞内病原体沙眼衣原体对糖酵解和糖异生碳源的总体转录反应。与自由活动的细菌相反,将碳源从葡萄糖改为谷氨酸或α-酮戊二酸对 C的整体基因转录影响很小。沙眼

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号