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The pap Operon of Avian Pathogenic Escherichia coli Strain O1:K1 Is Located on a Novel Pathogenicity Island

机译:禽致病性大肠杆菌O1:K1株的子宫颈操纵子位于一个新型致病岛上

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We have identified a 56-kb pathogenicity island (PAI) in avian pathogenic Escherichia coli strain O1:K1 (APEC-O1). This PAI, termed PAI IAPEC-O1, is integrated adjacent to the 3′ end of the pheV tRNA gene. It carries putative virulence genes of APEC (pap operon), other E. coli genes (tia and ireA), and a 1.5-kb region unique to APEC-O1. The kps gene cluster required for the biosynthesis of polysialic acid capsule was mapped to a location immediately downstream of this PAI.
机译:我们在禽类致病性大肠埃希氏菌O1:K1(APEC-O1)中鉴定了一个56 kb的致病岛。这种称为PAI I APEC-O1 的PAI与pheV tRNA基因的3'端相邻。它携带APEC( pap 操纵子)和其他 E的推定毒力基因。大肠杆菌基因( tia ireA ),以及一个APEC-O1特有的1.5 kb区域。将聚唾液酸胶囊的生物合成所需的 kps 基因簇定位到该PAI下游的位置。

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