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首页> 外文期刊>International Journal of Engineering Research and Applications >Optimization of Ultrasound-Assisted Extraction of Arbutin from Leaves of Pyrus elaeagnifolia Pallas ssp. elaeagnifolia (Rosaceae) by Response Surface Methodology
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Optimization of Ultrasound-Assisted Extraction of Arbutin from Leaves of Pyrus elaeagnifolia Pallas ssp. elaeagnifolia (Rosaceae) by Response Surface Methodology

机译：超声波辅助提取梨梨叶片中熊果苷的工艺优化。响应面方法学的蔷薇科（蔷薇科）

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Pyrus elaeagnifolia Pallas. ssp. elaeagnifolia is a medicinal plant used in traditional medicine for the treatment of various diseases in Turkey. The leaves of Pyrus elaeagnifolia ssp. elaeagnifolia are a rich source of arbutin, which is a naturally occurring derivative of hydroquinone. It is found in various plant species belonging to diverse families, such as Lamiaceae, Ericaceae, Saxifragaceae and Rosaceae. It inhibits tyrosinase and has been employed as a cosmetic skin whitening agent. In this study, Response Surface Methodology (RSM) using a Box Behnken Design (BBD) was employed to optimize the condition for extraction of arbutin from the leaves of Pyrus elaeagnifolia ssp. elaeagnifolia. Three influencing factors; methanol concentration, period of ultrasoundassisted extraction and extraction temperature were investigated in the ultrasonic aqueous extraction. The Response Surface Methodology was applied to optimize the extraction process focused on arbutin content with respect to the above influencing factors. The best combination of each significant factor was determined by RSM design and optimum pretreatment conditions for maximum arbutin content were established to be methanol concentration of 48.54 %, extraction time of 39.32 min. And extraction temperature of 43.71 0C. Under these conditions 5.37 % of arbutin content was observed experimentally, similar to the theoretical prediction of 5.30 %.
机译：梨elaeagnifolia Pallas。 ssp。 elaeagnifolia是一种用于传统医学的药用植物，可用于治疗土耳其的各种疾病。梨elaeagnifolia ssp的叶子。 elaeagnifolia是熊果苷的丰富来源，而熊果苷是对苯二酚的天然衍生物。它存在于属于不同科的各种植物物种中，例如唇形科，蓖麻科，虎耳草科和蔷薇科。它抑制酪氨酸酶，并已被用作化妆品美白剂。在这项研究中，采用Box Behnken设计（BBD）的响应表面方法（RSM）来优化从梨梨（Pyrus elaeagnifolia ssp）叶片中提取熊果苷的条件。 elaeagnifolia。三个影响因素;研究了超声水提法中甲醇的浓度，超声辅助提取的时间和提取温度。应用响应表面方法优化了针对上述影响因素的熊果苷含量的提取工艺。通过RSM设计确定每个重要因素的最佳组合，并确定最大熊果苷含量的最佳预处理条件为甲醇浓度为48.54％，提取时间为39.32分钟。且提取温度为43.71 0C。在这些条件下，实验观察到了5.37％的熊果苷含量，与5.30％的理论预测相似。

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