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首页> 外文期刊>International journal of infectious diseases : >Concordance between Vir and protein M gene (emm) types of Streptococcus pyogenes strains isolated from patients with invasive and non-invasive infections of Mexico
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Concordance between Vir and protein M gene (emm) types of Streptococcus pyogenes strains isolated from patients with invasive and non-invasive infections of Mexico

机译:从墨西哥的侵入性和非侵入性感染患者中分离出的化脓链球菌菌株的Vir和蛋白M基因(emm)类型之间的一致性

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Background: Identification of the emm types of Group A Streptococcus (GAS) strains associated to invasive infections and acute pharyngitis from Mexico by the protein M gene (emm) typing is crucial to evaluate the potential usefulness of the 26-valent candidate GAS vaccine developed in the U.S.A. In the same way, RFLP patterns of other method to type GAS strains such as Vir typing has been described to have a high concordance with specific emm types, but consistency has not been proven.
机译:背景:通过蛋白M基因(emm)分型鉴定与墨西哥的侵袭性感染和急性咽炎相关的A组链球菌(GAS)株的emm类型对于评估在美国开发的26价候选GAS疫苗的潜在用途至关重要。在美国,以同样的方式,已经描述了使用其他方法对GAS菌株进行分型的RFLP模式(如Vir分型)与特定的emm类型具有高度的一致性,但尚未证明一致性。

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