Production of Monoclonal Antibody Against Toxocara cati Second Stage Larvae and Its Application for the Detection of Circulating Antigens

M.Zibaei; S.M.Sadjjadi; B.Sarkari; S.Ishiyama; S.Uga

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Production of Monoclonal Antibody Against Toxocara cati Second Stage Larvae and Its Application for the Detection of Circulating Antigens

机译：弓形虫第二期幼虫单克隆抗体的生产及其在循环抗原检测中的应用

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Background: Toxocariasis is a zoonotic disease caused by the migration or presence of Toxocara canis or Toxocara cati larva in human tissues or organs. Human become infected by ingestion of soil or contaminated meat containing Toxocara larvae. Diagnosis of larval migrans is mainly based on detection of specific antibodies determined by enzyme-linked immunosorbent assay (ELISA), using larval excretory-secretory (ES) antigens. The aim of this study was to produce a monoclonal antibody against Toxocara cati second stage larvae antigens for possible immunodiagnosis of human toxocariasis.

机译：背景：弓形虫病是一种人畜共患病，是由于犬毛弓形虫或弓形虫的幼虫在人体组织或器官中迁移或存在所致。食人的土壤或含有弓形虫幼虫的污染肉类会感染人类。幼虫虫的诊断主要基于使用幼虫排泄-分泌（ES）抗原检测通过酶联免疫吸附测定（ELISA）确定的特异性抗体。这项研究的目的是生产一种抗弓形虫第二阶段幼虫抗原的单克隆抗体，用于可能对人弓形虫的免疫诊断。

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《International journal of infectious diseases :》 |2008年第1期|共2页
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M.Zibaei; S.M.Sadjjadi; B.Sarkari; S.Ishiyama; S.Uga;
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1. Production of monoclonal antibody against Toxocara cati second-stage larvae and its application for the detection of circulating antigens. [J] . Zibaei M, Sadjjadi SM, Ishiyama S, Hybridoma . 2010,第3期

机译：抗弓形虫第二级幼虫的单克隆抗体的生产及其在循环抗原检测中的应用。
2. Production of Monoclonal Antibody Against Toxocara cati Second Stage Larvae and Its Application for the Detection of Circulating Antigens [J] . M.Zibaei, S.M.Sadjjadi, B.Sarkari, International journal of infectious diseases : . 2008,第Supplementa1期

机译：弓形虫第二期幼虫单克隆抗体的生产及其在循环抗原检测中的应用
3. Monoclonal Antibody Against Toxocara cati Second-Stage Larvae [J] . Monoclonal antibodies in immunodiagnosis and immunotherapy . 2017,第3期

机译：对毒素的单克隆抗体反对Toxocara cati第二阶段幼虫
4. ANALYSIS OF SOMATIC, EXCRETORY/SECRETORY ANTIGENS AND PRODUCTION OF MONOCLONAL ANTIBODY OF TRICHURIS SUIS FOR IMMUNOLOGICAL DIAGNOSIS AND ANALYSIS BY ELISA FOR APPLICATION [C] . J.K. Lee, H.J. Yoon, J.T. Kim Congress of the International Pig Veterinary Society . 2000

机译：体细胞，排泄/分泌抗原与胰岛素肝癌素岩单克隆抗体的分析及ELISA施用分析
5. Characterization of Flagellin Antigen Using a Panel of Monoclonal Antibodies and Their Applications for Detection of Salmonella Based on Surface Plasmon Resonance [D] . Bhandari, Devendra Prasad. 2019

机译：用单克隆抗体面板及其基于表面等离子体共振检测沙门氏菌的鞭毛蛋白抗原的表征
6. Visceral larva migrans—an immunofluorescent examination of rabbit and human sera for antibodies to the ES antigens of the second stage larvae of Toxocara canis Toxocara cati and Toxascaris leonina (Nematoda) [O] . R. S. Hogarth-Scott 1966

机译：内脏幼虫移行—对兔和人血清中的弓形虫弓形虫和弓形虫（线虫）第二阶段幼虫的ES抗原进行免疫荧光检查
7. Production of Monoclonal Antibody Against Toxocara cati Second Stage Larvae and Its Application for the Detection of Circulating Antigens [O] . Zibaei M., Sadjjadi S.M., Sarkari B., 2008

机译：抗弓形虫第二期幼虫的单克隆抗体的生产及其在循环抗原检测中的应用
8. Schistosoma Mansoni: Detection of Circulating Antigens in Murine Schistosomiasisby Antigen-Capture Sandwich ELISA Using a Monoclonal Antibody [R] . Barsoum, I. S., Colley, D. G., Kamal, K. A. 1990

机译：schistosoma mansoni：使用单克隆抗体通过抗原捕获夹心ELIsa检测小鼠血吸虫病中的循环抗原

Production of Monoclonal Antibody Against Toxocara cati Second Stage Larvae and Its Application for the Detection of Circulating Antigens

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