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MicroRNAs as Diagnostic Biomarkers in Gastric Cancer

机译:MicroRNA作为胃癌的诊断生物标志物

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Considering the high mortality rates and the unfavorable prognosis of gastric cancer (GC) as well as the lack of a clinical predictive marker, which is sufficiently sensitive to GC, it is of great significance to investigate new sensitive and specific markers for GC diagnosis. MicroRNAs (miRNAs) could be a practical form of potential biomarkers in the diagnosis of human disease, and they are confirmed to be closely associated with GC. In this review, we discuss the recent research results that indicate the feasibility and clinical applications of miRNAs in GC. Although several challenges remain to be addressed, miRNAs have the potential to be applied in the diagnosis of GC.
机译:考虑到胃癌(GC)的高死亡率和不利的预后以及缺乏对GC足够敏感的临床预测标志物,研究新的敏感和特异性标志物对于GC诊断具有重要意义。微小RNA(miRNA)可能是诊断人类疾病的潜在生物标志物的实用形式,并且已确认它们与GC密切相关。在这篇综述中,我们讨论了最近的研究结果,这些结果表明了miRNA在GC中的可行性和临床应用。尽管仍有许多挑战有待解决,但miRNA仍有可能应用于GC的诊断。

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