...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>International journal of infectious diseases : >A Case-control Study of Risk Sources for Severe Fever with Thrombocytopenia Syndrome in Hubei Province, China
【24h】

A Case-control Study of Risk Sources for Severe Fever with Thrombocytopenia Syndrome in Hubei Province, China

机译：湖北省严重发热伴血小板减少综合征的危险源病例对照研究

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Background: Severe fever with thrombocytopenia syndrome (SFTS), an emerging infectious disease caused by a novel bunyavirus, was discovered in rural areas of Central China in 2009. Methods: A case-control study based on hospital data was applied to detect the potential risk sources for SFTS in SFTS-endemic counties in Hubei Province. Cases were defined as hospitalized SFTSV confirmed patients. Controls were randomly selected from non-SFTSV patients in the same hospital ward within 2 weeks of inclusion of the cases, and they were matched by age (+/- 5 years) and gender according to 1:2 matching condition. Results: 68 cases and 136 controls participated in this study. In multivariate analysis, ''Contact with cattle tick'' was the major risk source (Conditional Logistic Regression OR-MH=8.62, 95% CI=1.79-41.51), outdoor activities and working in weeds or hillside fields could increase risk of cattle tick contact and SFTS infection (Conditional Logistic Regression OR-MH=8.82, 95% CI=1.69-46.05, P value=0.01). Conclusion: Our results suggested cattle might be dominant hosts in SFTS-endemic regions in Hubei Province, which provided clues to transmission mechanism of ''vectors, host animals, and humans'', thus more effectively preventing and controlling the disease.
机译：背景：2009年在华中地区农村地区发现了由新型布尼亚病毒引起的新型传染病-血小板减少综合征（SFTS）的严重发烧。方法：基于医院数据的病例对照研究用于发现潜在风险湖北省SFTS流行县的SFTS来源。病例定义为经SFTSV确诊的住院患者。在纳入病例后2周内，从同一医院病房的非SFTSV患者中随机选择对照组，并根据年龄（+/- 5岁）和性别按照1：2匹配条件进行匹配。结果：68例和136名对照参加了这项研究。在多变量分析中，“与牛tick接触”是主要的风险来源（条件对数回归OR-MH = 8.62，95％CI = 1.79-41.51），户外活动以及在杂草或山坡地工作可能会增加牛的风险contact接触和SFTS感染（条件对数回归OR-MH = 8.82，95％CI = 1.69-46.05，P值= 0.01）。结论：我们的结果表明，牛可能是湖北省SFTS流行地区的主要宿主，这为“媒介，宿主动物和人”的传播机制提供了线索，从而更有效地预防和控制了该疾病。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号