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首页> 外文期刊>International Journal of Molecular Sciences >Role of Lipids in the Onset, Progression and Treatment of Periodontal Disease. A Systematic Review of Studies in Humans
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Role of Lipids in the Onset, Progression and Treatment of Periodontal Disease. A Systematic Review of Studies in Humans

机译：脂质在牙周疾病的发作，发展和治疗中的作用。对人类研究的系统回顾

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The risk of different oral problems (root caries, tooth mobility, and tooth loss) can be increased by the presence of periodontal disease, which has also been associated with a growing list of systemic diseases. The presence of some bacteria is the primary etiology of this disease; a susceptible host is also necessary for disease initiation. In this respect, the progression of periodontal disease and healing of the periodontal tissues can be modulated by nutritional status. To clarify the role of lipids in the establishment, progression, and/or treatment of this pathology, a systematic review was conducted of English-written literature in PubMed until May 2016, which included research on the relationship of these dietary components with the onset and progression of periodontal disease. According to publication type, randomized-controlled trials, cohort, case-control and cross-sectional studies were included. Among all the analyzed components, those that have any effect on oxidative stress and/or inflammation seem to be the most interesting according to current evidence. On one hand, there is quite a lot of information in favor of a positive role of n-3 fatty acids, due to their antioxidant and immunomodulatory effects. On the other hand, saturated fat-rich diets increase oxidative stress as well the as intensity and duration of inflammatory processes, so they must be avoided.
机译：牙周疾病的存在会增加发生各种口腔问题（龋齿，牙齿活动性和牙齿脱落）的风险，而牙周疾病也与越来越多的全身性疾病有关。一些细菌的存在是这种疾病的主要病因。易感宿主对于引发疾病也是必需的。在这方面，可以通过营养状况来调节牙周疾病的进展和牙周组织的愈合。为了阐明脂质在这种病理学的建立，发展和/或治疗中的作用，在PubMed上对英语文献进行了系统综述，直至2016年5月，其中包括对这些饮食成分与发病和发病之间关系的研究。牙周疾病的进展。根据出版物类型，包括随机对照试验，队列研究，病例对照研究和横断面研究。在所有分析的成分中，根据当前证据，对氧化应激和/或炎症有任何影响的那些成分似乎是最有趣的。一方面，由于n-3脂肪酸具有抗氧化和免疫调节作用，因此有很多信息支持n-3脂肪酸发挥积极作用。另一方面，饱和的富含脂肪的饮食会增加氧化应激以及炎症过程的强度和持续时间，因此必须避免。

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