Hep-2–Adherent Escherichia coli Strains Associated with Acute Infantile Diarrhea, S?o Paulo, Brazil

I. C. Scaletsky; Sandra HFabbricotti; Sueli OCSilva; Mauro BMorais; Ulysses Fagundes-Neto

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Hep-2–Adherent Escherichia coli Strains Associated with Acute Infantile Diarrhea, S?o Paulo, Brazil

机译：Hep-2 –急性小儿腹泻相关的大肠杆菌菌株，巴西圣保罗

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In this paired case-control study of infants with diarrhea in S.oPaulo, we examined the association between HEp-2–adherentEscherichia coli strains and diarrhea. We tested isolates fromstool specimens of infants with diarrhea and matched controlsin an HEp-2 cell adherence assay; we then hybridized isolateswith DNA probes and identified enteropathogenic E. coli(EPEC), enteroaggregative E. coli (EAEC), and diffusely adher-ent E. coli (DAEC). From 100 patient-control pairs, we isolated78 HEp-2–adherent strains; of these, 61 strains were singlepathogens identified in stools of infants with diarrhea. Whiletypical EPEC was significantly associated with diarrhea(p0.1). DAEC was isolated with equal frequency from patientsand controls (p>0.1).

机译：在这项关于圣保罗腹泻婴儿的配对病例对照研究中，我们研究了HEp-2粘附大肠杆菌菌株与腹泻之间的关系。我们在HEp-2细胞粘附试验中测试了腹泻婴儿粪便标本中的分离株以及相匹配的对照。然后，我们将分离物与DNA探针杂交并鉴定出肠致病性大肠杆菌（EPEC），肠聚集性大肠杆菌（EAEC）和弥散性粘附性大肠杆菌（DAEC）。从100对患者-对照对中，我们分离出78株HEp-2粘附菌株。其中，有61株是腹泻婴儿粪便中鉴定出的单一病原体。典型的EPEC与腹泻显着相关（p0.1）。从患者和对照组中均等分离出DAEC（p> 0.1）。

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《Emerging Infectious Diseases》 |2002年第8期|共4页
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I. C. Scaletsky; Sandra HFabbricotti; Sueli OCSilva; Mauro BMorais; Ulysses Fagundes-Neto;
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1. Prevalence of HEp-2 cell-adherent Escherichia coli and characterisation of enteroaggregative E-coli and chain-like adherent E-coli isolated from children with and without diarrhoea, in Londrina, Brazil [J] . Gioppo NMR., Vidotto MC., Linhares RE., FEMS Microbiology Letters . 2000,第2期

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2. Chronic Diarrhea, Hemorrhagic Colitis, and Hemolytic-Uremic Syndrome Associated with HEp-2 Adherent Escherichia coli in Adults Infected with Human Immunodeficiency Virus in Bangui, Central African Republic [J] . Christian Mossoro, Philippe Glaziou, Simon Yassibanda, Journal of Clinical Microbiology . 2002,第8期

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3. HEp-2 Cell-Adherent Escherichia coli and Intestinal Secretory Immune Response to Human Immunodeficiency Virus (HIV) in Outpatients with HIV-Associated Diarrhea [J] . John J. Mathewson, Bassam M. Salameh, Herbert L. DuPont, Clinical and diagnostic laboratory immunology . 1998,第1期

机译：HIV相关性腹泻门诊患者中HEp-2细胞粘附性大肠杆菌和对人类免疫缺陷病毒（HIV）的肠道分泌免疫反应
4. Two year monitoring of Escherichia coli and thermotolerant coliform densities in surface waters of Sao Paulo State, Brazil [C] . Hachich EM, Di Bari M, Rodrigues SR, . 2006

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5. Effect of the periphytic Escherichia coli and lake water bacterial population on the biofilm establishment of a Shiga toxin producing Escherichia coli O157:H7 strain [D] . MacDonald, Tallie Anne. 2015

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6. Hep-2–Adherent Escherichia coli Strains Associated with Acute Infantile Diarrhea São Paulo Brazil [O] . Isabel C. A. Scaletsky, Sandra H. Fabbricotti, Sueli O. C. Silva, 2002

机译：急性小儿腹泻相关的Hep-2粘附大肠杆菌菌株巴西圣保罗
7. Hep-2–Adherent Escherichia coli Strains Associated with Acute Infantile Diarrhea, São Paulo, Brazil [O] . Scaletsky, Isabel C. A., Fabbricotti, Sandra H., Silva, Sueli O. C., 2002

机译：急性小儿腹泻相关的Hep-2粘附性大肠杆菌菌株，巴西圣保罗
8. Tissue Culture-Adherent Escherichia Coli in Infantile Diarrhea [R] . Echeverria, P., Serichantalerg, O., Changchawalit, S., 1992

机译：组织培养 - 粘附大肠杆菌在小儿腹泻中的作用

Hep-2–Adherent Escherichia coli Strains Associated with Acute Infantile Diarrhea, S?o Paulo, Brazil

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