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Ceftazidime-Resistant Salmonella enterica, Morocco

机译：耐头孢他啶的沙门氏菌，摩洛哥

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To the Editor: Nontyphoidal salmonellosis (NTS) is a major food-borne illness worldwide. Extended-spectrum cephalosporins (ESCs) are currently preferred drugs for treatment of children with NTS. However, resis-tance to ESCs has emerged worldwide and has become a serious public health problem. This resistance is caused by production of various class A extend-ed-spectrum β-lactamases (ESBLs) and class C cephalosporinases in Sal-monella enterica (1).National surveillance systems, ideally based on integration of data for animals, food, and humans, are needed to develop strategies for con-taining antimicrobial drug resistance. Such systems are primarily based on a network of public or private clinical laboratories that refer Salmonella iso-lates to public health laboratories for identification. However, this laborato -ry-based surveillance system in devel-oping countries is hampered by cost constraints and poor access to qual-ity health facilities, resulting in a low rate of isolation of bacterial pathogens from patients having mild infections. These constraints account for the lack of data and underestimation of the number of NTS cases in many coun -tries, including Morocco
机译：致编辑：非伤寒沙门氏菌病（NTS）是世界范围内的主要食源性疾病。目前，广谱头孢菌素（ESC）是治疗NTS儿童的首选药物。然而，抗ESC的能力已经在世界范围内出现，并且已经成为严重的公共卫生问题。这种耐药性是由肠沙门氏菌产生的各种A级超广谱β-内酰胺酶（ESBLs）和C级头孢菌素酶引起的（1）。需要人类开发包含抗微生物药物耐药性的策略。这样的系统主要基于公共或私人临床实验室网络，该网络将沙门氏菌分离物推荐给公共卫生实验室进行鉴定。但是，在发展中国家，这种基于实验室的监视系统受到成本限制和难以获得优质医疗机构的阻碍，导致细菌病原体与轻度感染患者的隔离率较低。这些制约因素导致缺乏数据，而且在包括摩洛哥在内的许多国家都低估了NTS案件的数量。

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