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首页> 外文期刊>Emerging Infectious Diseases >Drug-Resistant Tuberculosis among Children, China, 2006–2015
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Drug-Resistant Tuberculosis among Children, China, 2006–2015

机译：2006-2015年中国儿童抗药性肺结核

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Microbial drug resistance has become a major public health concern worldwide. To acquire epidemiologic data on drug-resistant tuberculosis (DR TB) among children, a major cause of illness and death for this population, we conducted a retrospective study of 2006–2015 data from 36 TB prevention and control institutions in Shandong Province, China. A total of 14,223 new TB cases, among which children ( < 18 years of age) accounted for only 5.5%, were caused by culture-confirmed Mycobacterium tuberculosis . Among children with TB, 18.9% had DR TB and 6.9% had multidrug-resistant TB. Over the past decade, the percentage of DR TB; multidrug-resistant TB; and overall first-line drug resistance for isoniazid, rifampin, ethambutol, and streptomycin among children increased significantly (at least 12%). Understanding the long-term trends of DR TB among children can shed light on the performance of TB control programs, thereby contributing to global TB control.
机译：微生物耐药性已成为全球主要的公共卫生问题。为了获得儿童中耐药结核病（DR TB）的流行病学数据，这是该人群疾病和死亡的主要原因，我们对中国山东省的36 TB预防和控制机构进行了2006-2015年数据的回顾性研究。由培养证实的结核分枝杆菌引起的总共14,223例新结核病例，其中儿童（<18岁）仅占5.5％。在结核病儿童中，有18.9％患有DR结核病，而6.9％患有耐多药结核病。在过去十年中，DR TB的百分比;耐多药结核病;儿童中异烟肼，利福平，乙胺丁醇和链霉素的整体一线耐药性显着增加（至少12％）。了解儿童中DR TB的长期趋势可以阐明TB控制计划的绩效，从而有助于全球TB控制。

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