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Impact of Genotyping of Mycobacterium tuberculosis on Public Health Practice in Massachusetts

机译:结核分枝杆菌基因分型对马萨诸塞州公共卫生实践的影响

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Massachusetts was one of seven sentinel surveillance sites in the National Tuberculosis Genotyping andSurveillance Network. From 1996 through 2000, isolates from new patients with tuberculosis (TB) under-went genotyping. We describe the impact that genotyping had on public health practice in Massachusettsand some limitations of the technique. Through genotyping, we explored the dynamics of TB outbreaks,investigated laboratory cross-contamination, and identified Mycobacterium tuberculosis strains, transmis-sion sites, and accurate epidemiologic links. Genotyping should be used with epidemiologic follow-up toidentify how resources can best be allocated to investigate genotypic findings
机译:马萨诸塞州是国家结核病基因分型和监测网络中的七个定点监视站点之一。从1996年到2000年,对来自结核病(TB)新患者的分离株进行了基因分型。我们描述了基因分型对马萨诸塞州公共卫生实践的影响以及该技术的一些局限性。通过基因分型,我们探索了结核病暴发的动态,调查了实验室的交叉污染,并鉴定了结核分枝杆菌菌株,传播部位和准确的流行病学联系。基因分型应与流行病学随访一起使用,以识别如何最佳分配资源以调查基因型研究结果

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