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Ilheus Virus Isolate from a Human, Ecuador

机译：厄瓜多尔人的伊利乌斯病毒分离株

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To the Editor: Ilheus virus (ILHV) (genus Flavivirus in the Nta-ya antigenic complex) is most closely related to Rocio virus. However, anti-bodies produced during ILHV infec-tion cross-react in serologic assays to other . avivirus antigens, and ILHV was originally classifi ed in the Japa-nese encephalitis antigenic complex (1–3). ILHV is transmitted in an en-zootic cycle between birds and mos-quitoes. Since the fi rst isolation of ILHV from a pool of Aedes spp. and Psorophora spp. mosquitoes collected in 1944 at Ilheus City, on the east-ern coast of Brazil (4), isolates have been obtained in Central and South America and Trinidad, primarily from Psorophora ferox mosquitoes (5,6). ILHV is not associated with epidemic disease and has been only sporadical-ly isolated from humans (5,7–9). The clinical spectrum of human infections documented by virus isolation ranges from asymptomatic to signs of central nervous system involvement sugges-tive of encephalitis. Most commonly, patients exhibit a mild febrile illness accompanied by headache, myalgia, arthralgia, and photophobia, symptoms that may result in clinical diagnosis of dengue, Saint Louis encephalitis, yel-low fever, or in. uenza (7). Laboratory diagnosis of ILHV infection may be diffi cult, unless a virus isolate can be obtained, because of the cross-reactiv-ity in serologic assays to other . avivi-ruses that circulate in the same area, such as Rocio, dengue, yellow fever, and Saint Louis encephalitis viruses.On March 1, 2004, after 4 days of symptoms, a 20-year-old male sol-dier stationed in Lorocachi, Ecuador, was admitted to the Hospital de la IV División del Ejercito "Amazonas" in Puyo, Ecuador. Lorocachi is in the Amazonian province of Pastaza, of which Puyo is the capital. The patient had fever, rash, epistaxis, headache, myalgia, retroocular pain, nausea, vomiting, jaundice, sore throat, and abdominal pain
机译：致编辑：伊列乌斯病毒（ILHV）（Nta-ya抗原复合物中的黄病毒属）与Rocio病毒关系最密切。但是，ILHV感染期间产生的抗体在血清学检测中会与其他抗体交叉反应。禽病毒抗原和ILHV最初分类为Japa-nese脑炎抗原复合物（1-3）。 ILHV以鸟类和蚊子之间的动物园周期传播。自首次从伊蚊属中分离出ILHV以来。和假单胞菌属。 1944年在巴西东海岸的伊列乌斯市（Ilheus City）收集的蚊子（4），已从中美洲，南美洲和特立尼达（Trinidad）获得了分离株，主要是从费氏假单胞菌蚊子中分离得到的（5,6）。 ILHV与流行病无关，仅从人类偶发地分离出来（5,7–9）。通过病毒分离记录的人类感染的临床范围从无症状到中枢神经系统受累的脑炎迹象。最常见的是，患者表现出轻度的发热性疾病，并伴有头痛，肌痛，关节痛和畏光，这些症状可能导致登革热，圣路易斯脑炎，黄热病或uenza感染的临床诊断（7）。除非可以获得病毒分离株，否则ILHV感染的实验室诊断可能很难，因为血清学检测方法与其他方法具有交叉反应性。在同一地区传播的禽病毒，例如罗西奥病毒，登革热，黄热病和圣路易斯脑炎病毒。2004年3月1日，在症状持续4天后，一名20岁的男性溶胶-Dier进驻了罗罗基奇，厄瓜多尔，被送进了厄瓜多尔普约的“第四医院”。洛罗卡奇（Lorocachi）位于亚马逊省的帕斯塔萨（Pastaza），普约（Puyo）为首都。患者出现发烧，皮疹，鼻epi，头痛，肌痛，眼后痛，恶心，呕吐，黄疸，喉咙痛和腹痛

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