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Sphingomonas mucosissima Bacteremia in Patient with Sickle Cell Disease

机译:镰状细胞病患者的粘膜鞘氨醇单胞菌细菌血症

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To the Editor: The genus Sphin-gomonas was proposed by Yabuuchi et al. in 1990 (1) and amended by Takeuchi et al. in 1993 (2). It now has been subdivided into 4 sepa-rate genera: Sphingomonas sensu stricto, Sphingobium, Novosphingo-bium, and Sphingopyxis. The bacteria of the genus Sphingomonas are yel-low-pigmented, nonfermenting, gram-negative bacilli with a single polar . agellum; they are widely distributed in the natural environment, especially in water and soil (3). These bacteria are characterized by the presence of a unique sphingoglycolipid with the long-chain base—dihydrosphingosin, ubiquinone 10 (Q-10), and 2-hydrox-ymyristic acid (2-OH C14:0)—and the absence of 3-hydroxy fatty ac-ids (4). S. mucosissima was isolated and identifi ed in 2007 by Reddy and Garcia-Pichel from biologic soil crust samples collected from sandy arid soil in the US Colorado Plateau (5). Sphingomonas spp. are opportunis-tic pathogens and have recently been implicated in a variety of community-acquired and nosocomial infections, considered to originate from contami-nated hospital equipment or manipu-lation of some medical devices (3). The survival of Sphingomonas spp. in indoor dust particles as aerosols and their resistance to many disinfecting and toxic chemicals may explain their ability to colonize medical devices such as mechanical ventilators, cath-eters, and bronchofi beroscopes (6). In the past few years, these organisms, in particular S. paucimobilis, have been implicated in a variety of community-acquired and nosocomial infections
机译:致编者:Sphin-gomonas属是Yabuuchi等人提出的。 1990年(1)并由Takeuchi等修正。 1993年(2)。现在已将其细分为4个独立的属:鞘氨醇单胞菌,鞘氨醇单胞菌,新孢子菌单胞菌和鞘氨醇单胞菌。鞘氨醇单胞菌属的细菌是黄色低色素,非发酵,革兰氏阴性杆菌,具有单极性。阿格鲁姆它们广泛分布在自然环境中,特别是在水和土壤中(3)。这些细菌的特征是存在具有长链碱基的独特鞘氨醇脂-二氢鞘氨醇,泛醌10(Q-10)和2-羟基-羟丙酸(2-OH C14:0)-且不存在3-羟基脂肪酸(4)。 Reddy和Garcia-Pichel于2007年从美国科罗拉多高原的沙质干旱土壤中收集的生物土壤地壳样品中分离并鉴定了黏膜链球菌(5)。鞘氨醇单胞菌是机会性病原体,最近与各种社区获得性和医院感染有关,被认为是由污染的医院设备或某些医疗设备的操作引起的(3)。鞘氨醇单胞菌的存活。室内尘埃颗粒中的气溶胶及其对许多消毒和有毒化学物质的抵抗力可以解释其在医疗设备(例如机械呼吸机,导管和支气管镜)中的定殖能力(6)。在过去的几年中,这些生物,特别是沙门氏菌,与各种社区获得性和医院感染有关。

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