To the Editor: Since 2000,Salmonella enterica serovar ParatyphiB variant Java (S. Java) with resist-ance to antimicrobial drugs has beenisolated with increasing frequencyfrom patients in Scotland, England,Wales, and the Channel Islands. ForEngland, Wales, and the ChannelIslands, drug-resistant S. Java wasfound in humans: 25 in 2000, 36 in2001, 49 in 2002, and 4 in 2003(January 1–March 31). These isolatesmade up 35% of 325 strains of S. Javain human infections over the studyperiod (L.R. Ward, unpub. data). Arange of drug-resistant spectrums(R-types) have been observed,e.g., ASSpSuTm, ASSpSuTmCp,ASSpSuTTm, ACSSpSuT (A, ampi-cillin; C, chloramphenicol; S, strepto-mycin; Sp, spectinomycin; Su,sulphonamides; T, tetracyclines; Tm,trimethoprim; Cp, ciprofloxacin) (1).In general, isolates of S. Java of R-types ASSpSuTm, ASSpSuTmCp,and ASSpSuTTm, appear to be asso-ciated with imported poultry. In con-trast, infections with isolates of R-type ACSSpSuT have not been associ-ated with poultry, and organisms withthe ACSSpSuT resistant spectrumhave not been isolated from poultry inthe United Kingdom (R.H. Davies,pers. comm.).
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