Novel Cryptosporidium Genotypes in Sporadic Cryptosporidiosis Cases: First Report of Human Infections with a Cervine Genotype

C. S. Ong; Diane LEisler; Alireza Alikhani; Vicki WKFung; Joan Tomblin; William RBowie; Judith LIsaac-Renton

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Novel Cryptosporidium Genotypes in Sporadic Cryptosporidiosis Cases: First Report of Human Infections with a Cervine Genotype

机译：散发性隐孢子虫病病例中的新型隐孢子虫基因型：人类感染与子宫颈基因型的第一份报告。

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In this study, we genotyped parasites from the fecal specimens of sporadic cryptosporidiosis cases in Brit-ish Columbia from 1995 to 1999. Genotyping was conducted by polymerase chain amplification of theinternal transcribed spacer region, a hypervariable region in the 18S rRNA gene and the Cryptosporidiumoocyst wall protein gene. Subsequent analysis was by restriction fragment length polymorphism and DNAsequencing. We identified two new Cryptosporidium genotypes in humans. One of these genotypes hasbeen found recently in deer in New York state. The other genotype has not been identified in humans oranimals. These results have important implications for drinking water quality strategies, especially for com-munities that obtain drinking water supplies from surface sources located in forested regions with deerpopulations

机译：在这项研究中，我们对1995年至1999年间在不列颠哥伦比亚省的散发性隐孢子虫病病例的粪便标本中的寄生虫进行了基因分型。通过内部转录间隔区，18S rRNA基因的高变区和隐孢子虫卵囊壁的聚合酶链扩增进行基因分型。蛋白质基因。随后的分析是通过限制性片段长度多态性和DNA测序。我们在人类中发现了两种新的隐孢子虫基因型。这些基因型之一最近在纽约州的鹿中被发现。尚未在人类动物中鉴定出其他基因型。这些结果对饮用水质量战略具有重要意义，特别是对于从人口众多的森林地区的地表水源获取饮用水的社区

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《Emerging Infectious Diseases》 |2002年第3期|共6页
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C. S. Ong; Diane LEisler; Alireza Alikhani; Vicki WKFung; Joan Tomblin; William RBowie; Judith LIsaac-Renton;
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1. Human Cryptosporidiosis Diagnosed in Western Australia: a Mixed Infection with Cryptosporidium meleagridis, the Cryptosporidium Mink Genotype, and an Unknown Cryptosporidium Species [J] . Josephine S. Y. Ng-Hublin, Barry Combs, Brian MacKenzie, Journal of Clinical Microbiology . 2013,第7期

机译：在西澳大利亚诊断的人类隐孢子虫病：用Cryptiro孢子酰吡吡虫，隐孢子渣基因型和未知的隐孢子虫物种混合感染
2. Contemporary identification of previously reported novel Cryptosporidium isolates reveals Cryptosporidium bovis and the cervine genotype in sheep (Ovis aries) [J] . Kristin Elwin, Rachel M. Chalmers Parasitology Research . 2008,第5期

机译：对先前报道的新型隐孢子虫分离物的当代鉴定揭示了绵羊隐孢子虫和绵羊的基因型（Ovis aries）
3. Contemporary identification of previously reported novel Cryptosporidium isolates reveals Cryptosporidium bovis and the cervine genotype in sheep (Ovis aries). [J] . Elwin K, Chalmers RM Parasitology Research . 2008,第5期

机译：对先前报道的新型隐孢子虫分离物的当代鉴定揭示了牛隐孢子虫和绵羊（Ovis aries）的子宫颈基因型。
4. Prevalence of Human Papillomavirus Infection and Genotype Distribution Determined by the Cyclic-Catcher Melting Temperature Analysis in Korean Medical Checkup Population [C] . Yun-Jee Kim, Min-Jung Kwon, Hee-Yeon Woo, Molecular Medicine TRI-CON. . 2014

机译：人乳头瘤病毒感染和基因型分布的患病率韩国医学核肉熔融温度分析确定
5. Hepatitis C infection in injection drug users from southern China: Low viral clearance, multiple genotypes and mixed genotype infections. [D] . Garten, Rebecca JoAnne. 2005

机译：中国南部注射吸毒者的丙型肝炎感染：病毒清除率低，多种基因型和混合基因型感染。
6. Novel Cryptosporidium Genotypes in Sporadic Cryptosporidiosis Cases: First Report of Human Infections with a Cervine Genotype [O] . Corinne S. L. Ong, Diane L. Eisler, Alireza Alikhani, 2002

机译：偶发性隐孢子虫病病例中的新型隐孢子虫基因型：人类感染与子宫颈基因型的第一份报告。
7. Novel Cryptosporidium Genotypes in Sporadic Cryptosporidiosis Cases: First Report of Human Infections with a Cervine Genotype [O] . Ong, Corinne S. L., Eisler, Diane L., Alikhani, Alireza, 2002

机译：偶发性隐孢子虫病病例中的新型隐孢子虫基因型：人类感染与子宫颈基因型的第一份报告。

Novel Cryptosporidium Genotypes in Sporadic Cryptosporidiosis Cases: First Report of Human Infections with a Cervine Genotype

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