Persistence and variability of Stenotrophomonas maltophilia in Cystic Fibrosis Patients, Madrid, 1991-1998

S. Valdezate; Ana Vindel; Luis Maiz; Fernando Baquero; Hector Escobar; Rafael Cantón

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Persistence and variability of Stenotrophomonas maltophilia in Cystic Fibrosis Patients, Madrid, 1991-1998

机译：囊性纤维化患者嗜麦芽窄食单胞菌的持久性和变异性，马德里，1991-1998年

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During 1991 to 1998 at least one Stenotrophomonas maltophilia pulmonary infection was observed in 25 (24%) of 104 cystic fibrosis patients at the same unit of our hospital in Spain. Ribotyping and pulse-field gel electrophoresis (PFGE) characterization of 76 S. maltophilia isolates from these patients indicated an overall clonal incidence of 47.1%, reflecting new strains in 44% of patients with repeated positive cultures for S. maltophilia. Six patients with repeated episodes were persistently colonized (>6 months) with the same strain. S. maltophilia bacterial counts were higher (geometric mean, 2.9 x108 cfu/mL) in patients with repeated episodes than in those with a single episode (8.4 x104 cfu/mL, p16 years of age).

机译：在1991年至1998年期间，西班牙我们医院同一单位的104名囊性纤维化患者中至少有25名（24％）观察到了嗜麦芽窄食单胞菌的肺部感染。从这些患者中分离出的76株嗜乳链球菌的核糖体分型和脉冲场凝胶电泳（PFGE）表征表明，其总克隆发生率为47.1％，这反映了44％反复培养阳性的嗜麦芽胞菌的患者中出现了新菌株。六例反复发作的患者持续定植（> 6个月）同一菌株。反复发作患者的嗜麦芽胞杆菌嗜血菌计数高于单次发作患者（8.4 x104 cfu / mL，p16岁）（几何平均值，2.9 x108 cfu / mL）。

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《Emerging Infectious Diseases》 |2001年第1期|共10页
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S. Valdezate; Ana Vindel; Luis Maiz; Fernando Baquero; Hector Escobar; Rafael Cantón;
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1. Stenotrophomonas maltophilia strains from cystic fibrosis patients: Genomic variability and molecular characterization of some virulence determinants [J] . Nicoletti, M., Iacobino, A., Prosseda, G., International journal of medical microbiology: IJMM . 2011,第1期

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5. Variability in plant growth promoting properties among clinical and environmental isolates of Stenotrophomonas maltophilia. [D] . Domfeh, Yayra Ekui. 2015

机译：嗜麦芽窄食单胞菌的临床和环境分离株中促进植物生长的特性的变异性。
6. Persistence and variability of Stenotrophomonas maltophilia in cystic fibrosis patients Madrid 1991-1998. [O] . S. Valdezate, A. Vindel, L. Maiz, 2001

机译：囊性纤维化患者嗜麦芽窄食单胞菌的持久性和变异性马德里1991-1998年。
7. Persistence and variability of Stenotrophomonas maltophilia in cystic fibrosis patients, Madrid, 1991-1998. [O] . Valdezate, S., Vindel, A., Maiz, L., 2001

机译：囊性纤维化患者嗜麦芽窄食单胞菌的持久性和变异性，马德里，1991-1998年。

Persistence and variability of Stenotrophomonas maltophilia in Cystic Fibrosis Patients, Madrid, 1991-1998

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