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Clostridium difficile–associated Disease in the Elderly, United States

机译:美国老年人艰难梭菌相关疾病

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To the Editor: Zilberberg et al. (1) recently commented on the increase of hospitalizations for Clostridium dif-fi cile–associated disease (CDAD) and noted an increase in the case-fatality rate during 2000–2005. These fi ndings refer to the entire US adult population and agree with our observations for the elderly (>65 years of age). We as-sessed trends of CDAD in the elderly by using hospital billing data from the Centers for Medicare and Medicaid Services (CMS), which covers 98% of the elderly population (2). We ab-stracted all 1,054,125 hospitalization records that included C. diffi cile (In-ternational Classifi cation of Diseases, 9th revision, Clinical Modifi cation [ICD 9-CM], diagnosis code 008.45) in any of the 10 diagnosis code po-sitions for a 14-year period (1991–2004). We used elderly-population data from the 1990 and 2000 US Cen-sus. The ICD code for C. diffi cile was introduced in 1992. Case-patients in our dataset prior to this date represent severe illness and were hospitalized for >1 year and therefore were still in the hospital when the ICD code was introduced. We considered data from 1993 through 2004 because 1991 and 1992 are not representative due to in-troduction of the ICD code
机译:致编辑:Zilberberg等。 (1)最近评论了多发性梭状芽胞杆菌相关疾病(CDAD)住院治疗的增加,并指出2000-2005年间病死率增加。这些发现涉及整个美国成年人口,并且与我们对老年人(> 65岁)的观察结果一致。我们通过使用医疗保险和医疗补助中心(CMS)的医院账单数据评估了老年人CDAD的趋势,该数据覆盖了98%的老年人口(2)。我们摘录了10个诊断代码位置中任何一个的所有1,054,125个住院记录,其中包括艰难梭菌(国际疾病分类,第9版,临床修改[ICD 9-CM],诊断代码008.45)。为期14年(1991年至2004年)。我们使用了1990年和2000年美国Cen-sus的老年人口数据。艰难梭菌的ICD代码于1992年引入。在此日期之前,我们数据集中的病例患者患有严重疾病,住院时间超过1年,因此在引入ICD代码时仍在医院就诊。我们考虑了1993年至2004年的数据,因为1991和1992年由于引入了ICD代码而没有代表性

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