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首页> 外文期刊>Emerging Infectious Diseases >Shiga Toxin–producing Escherichia coli Serotype O78:H in Family, Finland, 2009
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Shiga Toxin–producing Escherichia coli Serotype O78:H in Family, Finland, 2009

机译：产生志贺毒素的大肠埃希菌，血清型O78：H，芬兰，2009年

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Shiga toxin–producing Escherichia coli (STEC) is a pathogen that causes gastroenteritis and bloody diarrhea but can lead to severe disease, such as hemolytic uremic syndrome (HUS). STEC serotype O78:H–: is rare among humans, and infections are often asymptomatic. We detected a sorbitol-fermenting STEC O78:H–stx1c:hlyA in blood and fecal samples of a 2-week-old boy who had bacteremia and HUS and in fecal samples of his asymptomatic family members. The phenotypic and genotypic characteristics and the virulence properties of this invasive STEC were investigated. Our fi ndings demonstrate that contrary to earlier suggestions, STEC under certain conditions can invade the human bloodstream. Moreover, this study highlights the need to implement appropriate diagnostic methods for identifying the whole spectrum of STEC strains associated with HUS
机译：产生志贺毒素的大肠杆菌（STEC）是一种病原体，可引起肠胃炎和血性腹泻，但可导致严重的疾病，例如溶血性尿毒症综合征（HUS）。 STEC O78：H–型血清型在人类中很少见，并且感染通常是无症状的。我们在一个有细菌血症和HUS的2周大男孩的血液和粪便样本中以及无症状家庭成员的粪便样本中检测到了山梨醇发酵型STEC O78：H–stx1c：hlyA。研究了该侵袭性STEC的表型和基因型特征以及毒力特性。我们的发现表明，与先前的建议相反，STEC在某些情况下会侵入人体血液。此外，本研究强调需要实施适当的诊断方法来鉴定与HUS相关的STEC菌株的整个谱图

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