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Skin and Soft Tissue Infections Caused by Methicillin-Resistant Staphylococcus aureus USA300 Clone

机译：耐甲氧西林金黄色葡萄球菌USA300克隆引起的皮肤和软组织感染

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Until recently, methicillin-resistant Staphylococcus au-reus (MRSA) has caused predominantly healthcare-asso-ciated infections. We studied MRSA infections and overall skin and soft tissue infections (SSTIs) in outpatients receiv-ing care at the Baltimore Veterans Affairs Medical Center Emergency Care Service during 2001–2005. We found an increase in MRSA infections, from 0.2 to 5.9 per 1,000 vis-its (p80% of MRSA infections were caused by USA300. In addition, SSTI visits increased from 20 to 61 per 1,000 visits (p<0.01). The proportion of SSTI cultures that yielded MRSA increased from 4% to 42% (p<0.01), while the proportion that yielded methicillin-sensi-tive S. aureus remained the same (10% to 13%, p = 0.5). The increase in community-associated MRSA infections and the overall increase in SSTIs in our population suggest that USA300 is becoming more virulent and has a greater propensity to cause SSTIs
机译：直到最近，耐甲氧西林的金黄色葡萄球菌（MRSA）仍主要导致与医疗相关的感染。我们在巴尔的摩退伍军人事务医疗中心急诊服务中心研究了接受门诊治疗的门诊患者的MRSA感染以及总体皮肤和软组织感染（SSTI），时间为2001-2005年。我们发现MRSA感染从每1000次访问增加到0.2个到5.9个（MRSA感染的80％是由USA300引起的。此外，SSTI访问从每1000个访问增加了20个到61个（p <0.01）。产生MRSA的SSTI培养物从4％增加到42％（p <0.01），而产生对甲氧西林敏感的金黄色葡萄球菌的比例保持不变（10％到13％，p = 0.5）。相关的MRSA感染和我们人群中SSTI的总体增加表明USA300的毒性越来越强，引起SSTI的倾向也更大

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