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首页> 外文期刊>Emerging Infectious Diseases >Rift Valley Fever Outbreak with East-Central African Virus Lineage in Mauritania, 2003
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Rift Valley Fever Outbreak with East-Central African Virus Lineage in Mauritania, 2003

机译：2003年毛里塔尼亚东非-中非病毒传承的裂谷热

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In October 2003, 9 human cases of hemorrhagic fever were reported in 3 provinces of Mauritania, West Afri-ca. Test results showed acute Rift Valley fever virus (RVFV) infection, and a fi eld investigation found recent circulation of RVFV with a prevalence rate of 25.5% (25/98) and 4 deaths among the 25 laboratory-confi rmed case-patients. Immuno-globulin M against RVFV was found in 46% (25/54) of do-mestic animals. RVFV was also isolated from the mosquito species Culex poicilipes. Genetic comparison of virion seg-ments indicated little variation among the strains isolated. However, phylogenetic studies clearly demonstrated that these strains belonged to the East-Central African lineage for all segments. To our knowledge, this is the fi rst time vi-ruses of this lineage have been observed in an outbreak in West Africa. Whether these strains were introduced or are endemic in West Africa remains to be determined
机译：2003年10月，在西阿菲里ca的毛里塔尼亚3个省报告了9例人类出血热病例。测试结果显示了急性裂谷热病毒（RVFV）感染，并且一项现场调查发现，最近的RVFV循环流行率为25.5％（25/98），在25名实验室确诊的病例患者中有4例死亡。 46％（25/54）的家养动物中发现了针对RVFV的免疫球蛋白M。 RVFV也从蚊虫库克斯库蚊中分离出来。病毒体片段的遗传比较表明分离出的菌株之间几乎没有差异。但是，系统发育研究清楚地表明，这些菌株在所有区段中均属于东非-中非血统。据我们所知，这是第一次在西非疫情中观察到这种血统的病毒。这些菌株是在西非引入还是地方流行尚待确定

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