Eight adult patients (ages 18–58, 5 women) with Buruli ulcer (BU) confi rmed by at least 2 diagnostic methods were seen in a 10-year period. Attempts to culture Mycobacterium ulcerans failed. Five patients came from jungle areas, and 3 from the swampy northern coast of Peru. The patients had 1–5 lesions, most of which were on the lower extremities. One patient had 5 clustered gluteal lesions; another patient had 2 lesions on a fi nger. Three patients were lost to follow-up. All 5 remaining patients had moderate disease. Diverse treatments (antituberculous drugs, World Health Organiza-tion [WHO] recommended antimicrobial drug treatment for BU, and for 3 patients, excision surgery) were successful. Only 1 patient (patient 7) received the specifi c drug treat-ment recommended by WHO. BU is endemic in Peru, al-though apparently infrequent. Education of populations and training of health workers are fi rst needed to evaluate and understand the full extent of BU in Peru
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